Browsing by Author "Wu, M"
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Competing Actions of Type 1 Angiotensin II Receptors Expressed on T Lymphocytes and Kidney Epithelium during Cisplatin-Induced AKI.
Crowley, Steven Daniel; Gurley, SB; Herrera, M; Jeffs, AD; Karlovich, NS; Nedospasov, SA; Patel, MB; ... (13 authors) (J Am Soc Nephrol, 2016-08)Inappropriate activation of the renin-angiotensin system (RAS) contributes to many CKDs. However, the role of the RAS in modulating AKI requires elucidation, particularly because stimulating type 1 angiotensin II (AT1) receptors ... -
Elevated PTH induces endothelial to chondrogenic transition in aortic endothelial cells.
Crowley, Steven Daniel; Liu, BC; Liu, H; Lv, LL; Ma, KL; Tang, RN; Wu, M; ... (8 authors) (Am J Physiol Renal Physiol, 2016-08-31)Previous studies have shown that increased parathyroid hormone (PTH) due to secondary hyperparathyroidism in chronic kidney disease accelerates the arteriosclerotic fibrosis and calcification. Although the underlying mechanisms ... -
Membrane binding of plasmid DNA and endocytic pathways are involved in electrotransfection of mammalian cells.
Wu, M; Yuan, F (PLoS One, 2011)Electric field mediated gene delivery or electrotransfection is a widely used method in various studies ranging from basic cell biology research to clinical gene therapy. Yet, mechanisms of electrotransfection are still ... -
Structure of the cold- And menthol-sensing ion channel TRPM8
Borschel, WF; Lander, GC; Lee, SY; Wu, M; Yin, Ying; Zubcevic, L (Science, 2018-01-12)Transient receptor potential melastatin (TRPM) cation channels are polymodal sensors that are involved in a variety of physiological processes. Within the TRPM family, member 8 (TRPM8) is the primary cold and menthol sensor ...