Browsing by Author "Wu, Wenting"
Now showing items 1-6 of 6
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Associations between smoking behavior-related alleles and the risk of melanoma.
(Oncotarget, 2016-07-26)Several studies have reported that cigarette smoking is inversely associated with the risk of melanoma. This study further tested whether incorporating genetic factors will provide another level of evaluation of mechanisms ... -
Effect of polymorphisms in XPD on clinical outcomes of platinum-based chemotherapy for Chinese non-small cell lung cancer patients.
(PloS one, 2012-01)PURPOSE: Xeroderma pigmentosum group D (XPD) codes for a DNA helicase involved in nucleotide excision repair that removes platinum-induced DNA damage. Genetic polymorphisms of XPD may affect DNA repair capacity and lead ... -
Genetic variants of PDGF signaling pathway genes predict cutaneous melanoma survival.
(Oncotarget, 2017-09)To investigate whether genetic variants of platelet-derived growth factor (PDGF) signaling pathway genes are associated with survival of cutaneous melanoma (CM) patients, we assessed associations of single-nucleotide ... -
Genetic Variants of the MDM2 Gene Are Predictive of Treatment-Related Toxicities and Overall Survival in Patients With Advanced NSCLC.
(Clin Lung Cancer, 2015-09)INTRODUCTION: Platinum agents can cause the formation of DNA adducts and induce apoptosis to eliminate tumor cells. The aim of the present study was to investigate the influence of genetic variants of MDM2 on chemotherapy-related ... -
Inverse Relationship between Vitiligo-Related Genes and Skin Cancer Risk.
(The Journal of investigative dermatology, 2018-09) -
Two-stage genome-wide association study identifies a novel susceptibility locus associated with melanoma.
(Oncotarget, 2017-03)Genome-wide association studies have identified 21 susceptibility loci associated with melanoma. These loci implicate genes affecting pigmentation, nevus count, telomere maintenance, and DNA repair in melanoma risk. Here, ...
