Browsing by Author "Yu, Chen"
Now showing items 1-4 of 4
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Dysregulated transcriptional responses to SARS-CoV-2 in the periphery.
McClain, Micah T; Constantine, Florica J; Henao, Ricardo; Liu, Yiling; Tsalik, Ephraim L; Burke, Thomas W; Steinbrink, Julie M; ... (20 authors) (Nature communications, 2021-02-17)SARS-CoV-2 infection has been shown to trigger a wide spectrum of immune responses and clinical manifestations in human hosts. Here, we sought to elucidate novel aspects of the host response to SARS-CoV-2 infection through ... -
Healthcare utilization and costs associated with dabigatran compared to warfarin treatment in newly diagnosed patients with non-valvular atrial fibrillation.
Francis, Kevin; Yu, Chen; Alvrtsyan, Hasmik; Sander, Stephen; Ghosh, Sabyasachi; Rao, Yajing; Sanchez, Herman; ... (8 authors) (Current medical research and opinion, 2015-12)<h4>Purpose</h4>Real-world healthcare resource utilization and costs were compared among patients with non-valvular atrial fibrillation (NVAF) receiving either dabigatran or warfarin.<h4>Methods</h4>A retrospective cohort ... -
Higher persistence in newly diagnosed nonvalvular atrial fibrillation patients treated with dabigatran versus warfarin.
Zalesak, Martin; Siu, Kimberly; Francis, Kevin; Yu, Chen; Alvrtsyan, Hasmik; Rao, Yajing; Walker, David; ... (11 authors) (Circulation. Cardiovascular quality and outcomes, 2013-09)<h4>Background</h4>Oral anticoagulation therapy is the primary tool in reducing stroke risk in patients with nonvalvular atrial fibrillation but is underused. Patients nonpersistent with therapy contribute to this underuse. ... -
Mucosal Associated Invariant T (MAIT) Cell Responses Differ by Sex in COVID-19.
Yu, Chen; Littleton, Sejiro; Giroux, Nicholas S; Mathew, Rose; Ding, Shengli; Kalnitsky, Joan; Yang, Yuchen; ... (21 authors) (Med (New York, N.Y.), 2021-04-13)Sexual dimorphisms in immune responses contribute to coronavirus disease 2019 (COVID-19) outcomes, yet the mechanisms governing this disparity remain incompletely understood. We carried out sex-balanced sampling of peripheral ...