Now showing items 1-2 of 2

    • Caspases: an ancient cellular sword of Damocles. 

      Boyce, M; Degterev, A; Yuan, J (Cell death and differentiation, 2004-01)
      Caspases are a family of cysteine proteases homologous to the Caenorhabditis elegans programmed cell death gene product CED-3. Caspases and their distant relatives, meta- and paracaspases, have been found in phylogenetically ...
    • The channel of death. 

      Degterev, A; Boyce, M; Yuan, J (The Journal of cell biology, 2001-11-26)
      The proapoptotic members of the Bcl-2 family have been proposed to participate in the formation of a channel that releases these apoptogenic factors when mitochondria receive apoptotic signals. A recent study provides the ...