Browsing by Author "Zeng, Yi"
Now showing items 1-16 of 16
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A U-shaped Association Between Blood Pressure and Cognitive Impairment in Chinese Elderly.
(Journal of the American Medical Directors Association, 2017-02)<h4>Objectives</h4>Higher or lower blood pressure may relate to cognitive impairment, whereas the relationship between blood pressure and cognitive impairment among the elderly is not well-studied. The study objective was ... -
Associations between superoxide dismutase, malondialdehyde and all-cause mortality in older adults: a community-based cohort study.
(BMC geriatrics, 2019-04-15)<h4>Background</h4>Oxidative stress is an important theory of aging but population-based evidence has been lacking. This study aimed to evaluate the associations between biomarkers of oxidative stress, including plasma superoxide ... -
Demographics, phenotypic health characteristics and genetic analysis of centenarians in China.
(Mech Ageing Dev, 2016-12-28)After a brief introduction to the background, significance and unique features of the centenarian population in China, we describe the Chinese Longitudinal Healthy Longevity Study (CLHLS), which is the world's largest study ... -
Development and Validation of the Disability Index Among Older Adults.
(The journals of gerontology. Series A, Biological sciences and medical sciences, 2023-01)<h4>Background</h4>With the rapid population aging, the challenge to provide care for disabled older adults is becoming bigger. This study aims to develop the Disability Index (DI) to assess disability to indicate care needs, ... -
Gender-dependent association of body mass index and waist circumference with disability in the Chinese oldest old.
(Obesity (Silver Spring), 2014-08)OBJECTIVES: To explore associations of BMI and waist circumference (WC) with disability among the Chinese oldest old. METHODS: The 5,495 oldest old in the sixth wave of Chinese Longitudinal Healthy Longevity Study conducted ... -
Incorporating biomarkers into the study of socio-economic status and health among older adults in China.
(SSM - population health, 2017-12)The social gradient in health - that individuals with lower SES have worse health than those with higher SES- is welldocumented using self-reports of health in more developed countries. Less is known about the relationship ... -
Interactions between life stress factors and carrying the APOE4 allele adversely impact self-reported health in old adults.
(The Journals of Gerontology Series A: Biological Sciences and Medical Sciences, 2011-10)Based on the multiple logistic regression analysis of data from a random sample of 1,023 old adults collected in Taiwan in 2000, we found that interactions between carrying the APOE4 allele and one of four life stress factors ... -
Interactions between social/ behavioral factors and ADRB2 genotypes may be associated with health at advanced ages in China.
(BMC Geriatr, 2013-09-09)BACKGROUND: Existing literature indicates that ADRB2 gene is associated with health and longevity, but none of previous studies investigated associations of carrying the ADRB2 minor alleles and interactions between ADRB2 ... -
Low-density lipoprotein cholesterol was inversely associated with 3-year all-cause mortality among Chinese oldest old: data from the Chinese Longitudinal Healthy Longevity Survey.
(Atherosclerosis, 2015-03)<h4>Objective</h4>Low-density lipoprotein cholesterol (LDL-C) is a risk factor for survival in middle-aged individuals, but conflicting evidence exists on the relationship between LDL-C and all-cause mortality among the ... -
Novel loci and pathways significantly associated with longevity.
(Sci Rep, 2016-02-25)Only two genome-wide significant loci associated with longevity have been identified so far, probably because of insufficient sample sizes of centenarians, whose genomes may harbor genetic variants associated with health ... -
Older Parents Benefit More in Health Outcome From Daughters' Than Sons' Emotional Care in China.
(J Aging Health, 2016-12)OBJECTIVE: To examine whether older parents in China would benefit more from daughters' care than from sons' emotional care. METHOD: Analysis of the unique data sets of the Chinese Longitudinal Healthy Longevity Survey conducted ... -
PhenX RISING: real world implementation and sharing of PhenX measures.
(BMC Med Genomics, 2014-03-20)BACKGROUND: The purpose of this manuscript is to describe the PhenX RISING network and the site experiences in the implementation of PhenX measures into ongoing population-based genomic studies. METHODS: Eighty PhenX measures ... -
Prevalence and Risk Factors of Atrial Fibrillation in Chinese Elderly: Results from the Chinese Longitudinal Healthy Longevity Survey.
(Chinese medical journal, 2015-09)<h4>Background</h4>Prevalence of atrial fibrillation (AF) is increasing as the world ages. AF is associated with higher risk of mortality and disease, including stroke, hypertension, heart failure, and dementia. Prevalence ... -
Survival, disabilities in activities of daily living, and physical and cognitive functioning among the oldest-old in China: a cohort study.
(Lancet, 2017-04-22)BACKGROUND: The oldest-old (those aged ≥80 years) are the most rapidly growing age group globally, and are most in need of health care and assistance. We aimed to assess changes in mortality, disability in activities of ... -
Vitamin D levels and cognition in elderly adults in China.
(Journal of the American Geriatrics Society, 2014-11)<h4>Objectives</h4>To evaluate the association between vitamin D level and cognitive impairment in individuals aged 60 and older.<h4>Design</h4>Cross-sectional cohort study.<h4>Setting</h4>Chinese Longitudinal Healthy Longevity ... -
Vitamin D Levels and the Risk of Cognitive Decline in Chinese Elderly People: the Chinese Longitudinal Healthy Longevity Survey.
(The journals of gerontology. Series A, Biological sciences and medical sciences, 2016-10)<h4>Background</h4>Vitamin D has a neuroprotective function, potentially important for the prevention of cognitive decline. Prospective studies from Western countries support an association between lower vitamin D level ...
