Browsing by Author "Zhang, Fengyu"
Now showing items 1-12 of 12
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A caution in association of ABO blood group with COVID-19
Hughes, Claude; Zhang, Fengyu (Global Clinical and Translational Research, 2020-06-10) -
Beyond p-value: the Rigor and Power of Study
Zhang, Fengyu; Hughes, Claude (Global Clinical and Translational Research, 2020-01-10)<jats:p>There have been a series of recent discussions and debates on the p-value and statistical significance. These discussions, including publications of more than 40 papers in a special issue of the American Statistician, ... -
Clinical Epidemiology of Coronavirus Disease 2019: Defined on Current Research
Hughes, Claude; Zhang, Fengyu (Global Clinical and Translational Research, 2020-07-25)<jats:p>Coronavirus disease 2019 (COVID-19) is a new infectious respiratory disease that has caused the ongoing global pandemic. The primary purpose of this article is to describe evolving clinical epidemiology of COVID-19, ... -
Ecological Analysis of Gastroschisis Incidence Decline in Liaoning, China, 2006-2016
Li, Ruiping; Zhang, Fengyu; Hughes, Claude; Li, Jianxin (Global Clinical and Translational Research, 2020-12-30)<jats:p>Background: A gastroschisis incidence decline has recently been reported in Liaoning, China, from 2006-2015; we suspect that this decline could be associated with the fall in industrial manufacturing activities. Methods: ... -
Human genetic risk of treatment with antiviral nucleoside analog drugs that induce lethal mutagenesis: The special case of molnupiravir.
Waters, Michael D; Warren, Stafford; Hughes, Claude; Lewis, Philip; Zhang, Fengyu (Environmental and molecular mutagenesis, 2022-01)This review considers antiviral nucleoside analog drugs, including ribavirin, favipiravir, and molnupiravir, which induce genome error catastrophe in SARS-CoV or SARS-CoV-2 via lethal mutagenesis as a mode of action. In ... -
Interactions between life stress factors and carrying the APOE4 allele adversely impact self-reported health in old adults.
Zeng, Yi; Hughes, Claude L; Lewis, Megan A; Li, Jianxin; Zhang, Fengyu (The Journals of Gerontology Series A: Biological Sciences and Medical Sciences, 2011-10)Based on the multiple logistic regression analysis of data from a random sample of 1,023 old adults collected in Taiwan in 2000, we found that interactions between carrying the APOE4 allele and one of four life stress factors ... -
Interactions between social/ behavioral factors and ADRB2 genotypes may be associated with health at advanced ages in China.
Zeng, Yi; Cheng, Lingguo; Zhao, Ling; Tan, Qihua; Feng, Qiushi; Chen, Huashuai; Shen, Ke; ... (16 authors) (BMC Geriatr, 2013-09-09)BACKGROUND: Existing literature indicates that ADRB2 gene is associated with health and longevity, but none of previous studies investigated associations of carrying the ADRB2 minor alleles and interactions between ADRB2 ... -
Interpretation of the Environmental Impact on Autism Spectrum Disorder
Zhang, Fengyu; Hughes, Claude (Global Clinical and Translational Research, 2019-09-30)<jats:p>Comments on Maternal exposure to triclosan constitutes a yet unrecognized risk factor for autism spectrum disorders. Cell Res. 2019. https://www.nature.com/articles/s41422-019-0220-1, PMID:31462724</jats:p> -
New Journal Launch: Global Clinical and Translational Research
Hughes, Claude; Zhang, Fengyu (Global Clinical and Translational Research, 2019-03-30)<jats:p>We are proud to announce the launch of Global Clinical and Translational Research, a new journal that aims to promote clinical and translational research in the genomic era from a global perspective. The journal ... -
Prenatal Environment and Perinatal Factors Associated with Autism Spectrum Disorder
Ou, Jianjun; Shen, Yidong; Li, Yamin; Xu, Guanglei; Liu, Huaqing; He, Yiqun; Guo, Hui; ... (12 authors) (Global Clinical and Translational Research, 2019-09-30)<jats:p>Background: Both genetic and epidemiological studies have indicated that environmental factors play an essential role in the development of autism spectrum disorder (ASD). We conducted this study to identify maternal ... -
Reply to Comments on "Beyond P-value: the Rigor and Power of Study"
Zhang, Fengyu; Hughes, Claude (Global Clinical and Translational Research, 2020-01-10)<jats:p>We received commentaries that included comments on our paper. Here we provide replies to the comments in the order received. To avoid confusion, we made a revision in the Table 1 to assure that level of significance ... -
Reporting standards for clinical and translational research
Hughes, Claude; Zhang, Fengyu (Global Clinical and Translational Research, 2019-04-16)