Browsing by Author "Zhao, L-X"

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β-arrestin-2 regulates NMDA receptor function in spinal lamina II neurons and duration of persistent pain.

Chen, Gang; Xie, R-G; Gao, Y-J; Xu, Zhenzhong; Zhao, L-X; Bang, Sangsu; Berta, T; ... (11 authors) (Nat Commun, 2016-08-19)

Mechanisms of acute pain transition to chronic pain are not fully understood. Here we demonstrate an active role of β-arrestin 2 (Arrb2) in regulating spinal cord NMDA receptor (NMDAR) function and the duration of pain. ...