ALERT: This system is being upgraded on Tuesday December 12. It will not be available for use for several hours that day while the upgrade is in progress. Deposits to DukeSpace will be disabled on Monday December 11, so no new items are to be added to the repository while the upgrade is in progress. Everything should be back to normal by the end of day, December 12.

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    • CD20 deficiency in humans results in impaired T cell-independent antibody responses. 

      Kuijpers, Taco W; Bende, Richard J; Baars, Paul A; Grummels, Annette; Derks, Ingrid AM; Dolman, Koert M; Beaumont, Tim; ... (11 authors) (J Clin Invest, 2010-01)
      CD20 was the first B cell differentiation antigen identified, and CD20-specific mAbs are commonly used for the treatment of B cell malignancies and autoantibody-mediated autoimmune diseases. Despite this the role of CD20 ...