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Browsing by Subject "Administration, Inhalation"
Now showing items 1-12 of 12
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Assessing acute systemic effects of an inhaled drug with serial echocardiography: a placebo-controlled comparison of inhaled and intravenous dihydroergotamine.
(Drug Des Devel Ther, 2013)OBJECTIVE: MAP0004 is an investigational product which delivers dihydroergotamine (DHE) through the lung via a breath-synchronized metered dose inhaler. The objective of this study was to compare the acute effects of orally ... -
Donor pretreatment with nebulized complement C3a receptor antagonist mitigates brain-death induced immunological injury post-lung transplant.
(American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 2018-10)Donor brain death (BD) is an inherent part of lung transplantation (LTx) and a key contributor to ischemia-reperfusion injury (IRI). Complement activation occurs as a consequence of BD in other solid organ Tx and exacerbates ... -
Epithelial injury and interstitial fibrosis in the proximal alveolar regions of rats chronically exposed to a simulated pattern of urban ambient ozone.
(Toxicology and applied pharmacology, 1992-08)Electron microscopic morphometry was used to study the development of lung injury during and after chronic (78 weeks) exposure to a pattern of ozone (O3) designed to simulate high urban ambient concentrations that occur ... -
High prevalence of substance use disorders among adolescents who use marijuana and inhalants.
(Drug and alcohol dependence, 2005-04)BACKGROUND: We examined the association between the use of inhalants, marijuana, and other drugs and recent DSM-IV substance use disorders among adolescents aged 12-17 years. METHODS: Data were drawn from 2000 to 2001 National ... -
Inhalant abuse and dependence among adolescents in the United States.
(Journal of the American Academy of Child and Adolescent Psychiatry, 2004-10)To examine the patterns of inhalant use and correlates of the progression from inhalant use to abuse and dependence among adolescents aged 12 to 17.Study data were drawn from the 2000 and 2001 National Household Surveys ... -
Inhalant use and disorders among adults in the United States.
(Drug and alcohol dependence, 2006-10)To examine the patterns of adult inhalant use and correlates of inhalant use disorder.We drew study data from the 2002 and 2003 National Surveys on Drug Use and Health (NSDUH). We used logistic regression to identify the ... -
Is inhalant use a risk factor for heroin and injection drug use among adolescents in the United States?
(Addictive behaviors, 2007-02)We examined whether inhalant use was associated with heroin and injection drug use (IDU) among adolescents aged 12 to 17 in the United States.Data were drawn from the 2002/2003 administrations of the National Survey on Drug ... -
Pharmacologically augmented S-nitrosylated hemoglobin improves recovery from murine subarachnoid hemorrhage.
(Stroke, 2011-02)<h4>Background and purpose</h4>S-nitrosylated hemoglobin (S-nitrosohemoglobin) has been implicated in the delivery of O(2) to tissues through the regulation of microvascular blood flow. This study tested the hypothesis that ... -
PINOT NOIR: pulmonic insufficiency improvement with nitric oxide inhalational response.
(J Cardiovasc Magn Reson, 2013-09-04)BACKGROUND: Tetralogy of Fallot (TOF) repair and pulmonary valvotomy for pulmonary stenosis (PS) lead to progressive pulmonary insufficiency (PI), right ventricular enlargement and dysfunction. This study assessed whether ... -
Psychiatric disorders in inhalant users: results from The National Epidemiologic Survey on Alcohol and Related Conditions.
(Drug and alcohol dependence, 2007-05)To examine the prevalence and correlates of mood, anxiety, and personality disorders among lifetime inhalant users.Statistical analyses were based on data from the 2001-2002 National Epidemiologic Survey on Alcohol and Related ... -
Regional Gas Exchange Measured by 129 Xe Magnetic Resonance Imaging Before and After Combination Bronchodilators Treatment in Chronic Obstructive Pulmonary Disease.
(Journal of magnetic resonance imaging : JMRI, 2021-09)<h4>Background</h4>Hyperpolarized 129 Xe magnetic resonance imaging (MRI) provides a non-invasive assessment of regional pulmonary gas exchange function. This technique has demonstrated that chronic obstructive pulmonary ... -
Use of nitrite inhalants ("poppers") among American youth.
(The Journal of adolescent health : official publication of the Society for Adolescent Medicine, 2005-07)PURPOSE: We examined the patterns and correlates of nitrite inhalant use among adolescents aged 12 to 17 years. METHODS: Study data were drawn from the 2000 and 2001 National Household Surveys on Drug Abuse. Logistic regression ...
