Browsing by Subject "Age Factors"
Now showing items 1-20 of 163
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A cohort study of 4,190 patients treated with low-intensity pulsed ultrasound (LIPUS): findings in the elderly versus all patients.
(BMC Musculoskelet Disord, 2015-03-01)BACKGROUND: Patient age is one of many potential risk factors for fracture nonunion. Our hypothesis is that older patients (≥ 60) with fracture risk factors treated with low-intensity pulsed ultrasound (LIPUS) have similar ... -
A dimensional approach to understanding severity estimates and risk correlates of marijuana abuse and dependence in adults.
(International journal of methods in psychiatric research, 2012-06)While item response theory (IRT) research shows a latent severity trait underlying response patterns of substance abuse and dependence symptoms, little is known about IRT-based severity estimates in relation to clinically ... -
A Longitudinal Cohort Study of Malaria Exposure and Changing Serostatus in a Malaria Endemic Area of Rural Tanzania
(Malaria Journal, 2017-08-02)<h4>Background</h4>Measurements of anti-malarial antibodies are increasingly used as a proxy of transmission intensity. Most serological surveys are based on the use of cross-sectional data that, when age-stratified, approximates ... -
A meta-analysis of four genome-wide association studies of survival to age 90 years or older: the Cohorts for Heart and Aging Research in Genomic Epidemiology Consortium.
(J Gerontol A Biol Sci Med Sci, 2010-05)BACKGROUND: Genome-wide association studies (GWAS) may yield insights into longevity. METHODS: We performed a meta-analysis of GWAS in Caucasians from four prospective cohort studies: the Age, Gene/Environment Susceptibi... -
Accelerated epigenetic age as a biomarker of cardiovascular sensitivity to traffic-related air pollution.
(Aging, 2020-12)<h4>Background</h4>Accelerated epigenetic age has been proposed as a biomarker of increased aging, which may indicate disruptions in cellular and organ system homeostasis and thus contribute to sensitivity to environmental ... -
Aerobic exercise and neurocognitive performance: a meta-analytic review of randomized controlled trials.
(Psychosom Med, 2010-04)OBJECTIVES: To assess the effects of aerobic exercise training on neurocognitive performance. Although the effects of exercise on neurocognition have been the subject of several previous reviews and meta-analyses, they have ... -
Age mediation of frontoparietal activation during visual feature search.
(Neuroimage, 2014-11-15)Activation of frontal and parietal brain regions is associated with attentional control during visual search. We used fMRI to characterize age-related differences in frontoparietal activation in a highly efficient feature ... -
Age of first drunkenness and risks for all-cause mortality: A 27-year follow-up from the epidemiologic catchment area study.
(Drug and alcohol dependence, 2017-07)Early-onset drunkenness is associated with an increased risk of developing an alcohol use disorder (AUD), which predicts excess mortality risk. Here, we estimated mortality risk for drinkers with and without early drunkenness.For ... -
Age patterns of incidence of geriatric disease in the U.S. elderly population: Medicare-based analysis.
(J Am Geriatr Soc, 2012-02)OBJECTIVES: To use the Medicare Files of Service Use (MFSU) to evaluate patterns in the incidence of aging-related diseases in the U.S. elderly population. DESIGN: Age-specific incidence rates of 19 aging-related diseases ... -
Age, gender, and cancer but not neurodegenerative and cardiovascular diseases strongly modulate systemic effect of the Apolipoprotein E4 allele on lifespan.
(PLoS Genet, 2014-01)Enduring interest in the Apolipoprotein E (ApoE) polymorphism is ensured by its evolutionary-driven uniqueness in humans and its prominent role in geriatrics and gerontology. We use large samples of longitudinally followed ... -
Age-related differences in the neural bases of phonological and semantic processes in the context of task-irrelevant information.
(Cognitive, affective & behavioral neuroscience, 2019-08)As we age we have increasing difficulty with phonological aspects of language production. Yet semantic processes are largely stable across the life span. This suggests a fundamental difference in the cognitive and potentially ... -
Age-related differences in the neural bases of phonological and semantic processes.
(Journal of cognitive neuroscience, 2014-12)Changes in language functions during normal aging are greater for phonological compared with semantic processes. To investigate the behavioral and neural basis for these age-related differences, we used fMRI to examine younger ... -
Age-related slowing in the retrieval of information from long-term memory.
(Journal of gerontology, 1985-03)The present experiment investigated adult age differences in the retrieval of information from long-term memory. Each trial required a decision regarding the synonymy of two visually presented words. On the yes-response ... -
Age-specific differences in oncogenic pathway deregulation seen in human breast tumors.
(PLoS One, 2008-01-02)PURPOSE: To define the biology driving the aggressive nature of breast cancer arising in young women. EXPERIMENTAL DESIGN: Among 784 patients with early stage breast cancer, using prospectively-defined, age-specific cohorts ... -
Alcohol and drug use disorders among adults in emergency department settings in the United States.
(Annals of emergency medicine, 2012-08)Improving identification and treatment for substance use disorders is a national priority, but data about various drug use disorders encountered in emergency departments (EDs) are lacking. We examine past-year substance ... -
Alcohol dependence and use of treatment services among women in the community.
(The American journal of psychiatry, 2004-10)OBJECTIVE:This study examined the extent and characteristics of alcohol dependence and the perceived need for and use of alcohol treatment services among women compared with men in a nonclinical sample of adults 18-64 years ... -
Amino acid racemization reveals differential protein turnover in osteoarthritic articular and meniscal cartilages.
(Arthritis Res Ther, 2009)INTRODUCTION: Certain amino acids within proteins have been reported to change from the L form to the D form over time. This process is known as racemization and is most likely to occur in long-lived low-turnover tissues ... -
An age-structured extension to the vectorial capacity model.
(PLoS One, 2012)BACKGROUND: Vectorial capacity and the basic reproductive number (R(0)) have been instrumental in structuring thinking about vector-borne pathogen transmission and how best to prevent the diseases they cause. One of the ... -
An item response theory analysis of DSM-IV criteria for hallucinogen abuse and dependence in adolescents.
(Addictive behaviors, 2010-03)AIM:This study applied both item response theory (IRT) and multiple indicators-multiple causes (MIMIC) methods to evaluate item-level psychometric properties of diagnostic questions for hallucinogen use disorders (HUDs), ... -
An item response theory modeling of alcohol and marijuana dependences: a National Drug Abuse Treatment Clinical Trials Network study.
(Journal of studies on alcohol and drugs, 2009-05)OBJECTIVE:The aim of this study was to examine psychometric properties of the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (DSM-IV), diagnostics criteria for alcohol and marijuana dependences among ...
