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Browsing by Subject "Analgesics, Opioid"
Now showing items 1-20 of 33
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Addressing the Opioid Crisis: A Dynamic Case-Based Module Set for Interprofessional Educators, Learners, and Clinicians.
(MedEdPORTAL : the journal of teaching and learning resources, 2022-01)<h4>Introduction</h4>In 2017, the opioid crisis was declared a public health emergency in the United States. The CDC has called for a multifaceted, collaborative approach to address the opioid epidemic. Though many resources ... -
Amitifadine, a triple reuptake inhibitor, reduces self-administration of the opiate remifentanil in rats.
(Psychopharmacology, 2020-06)<h4>Rationale</h4>A variety of neural systems are involved in drug addiction, and some of these systems are shared across different addictive drugs. We have found several different types of drug treatments that successfully ... -
Associations between cigarette smoking and pain among veterans.
(Epidemiologic reviews, 2015-01-16)Individuals with chronic pain often report using cigarettes to cope, and smoking and chronic pain appear prevalent among US veterans. Pain may be a barrier to cigarette cessation and abstinence in this population. Because ... -
Buprenorphine compared with methadone to treat pregnant women with opioid use disorder: a systematic review and meta-analysis of safety in the mother, fetus and child.
(Addiction (Abingdon, England), 2016-12)<h4>Aims</h4>To assess the safety of buprenorphine compared with methadone to treat pregnant women with opioid use disorder.<h4>Methods</h4>We searched PubMed, Embase and the Cochrane Library from inception to February 2015 ... -
Buprenorphine for prescription opioid addiction in a patient with depression and alcohol dependence.
(The American journal of psychiatry, 2011-07) -
Construct and differential item functioning in the assessment of prescription opioid use disorders among American adolescents.
(Journal of the American Academy of Child and Adolescent Psychiatry, 2009-05)OBJECTIVE:To examine the psychometric properties of diagnostic criteria for prescription analgesic opioid use disorders (OUDs) and to identify background predictors of a latent continuum for OUD liability. METHOD:Data were ... -
Development and Validation of a Model for Opioid Prescribing Following Gynecological Surgery.
(JAMA network open, 2022-07)<h4>Importance</h4>Overprescription of opioid medications following surgery is well documented. Current prescribing models have been proposed in narrow patient populations, which limits their generalizability.<h4>Objective</h4>To ... -
Development and validation of an electronic health records-based opioid use disorder algorithm by expert clinical adjudication among patients with prescribed opioids.
(Pharmacoepidemiology and drug safety, 2023-05)<h4>Background</h4>In the US, over 200 lives are lost from opioid overdoses each day. Accurate and prompt diagnosis of opioid use disorders (OUD) may help prevent overdose deaths. However, international classification of ... -
Differential behavioral functioning in the offspring of rats with high vs. low self-administration of the opioid agonist remifentanil.
(European journal of pharmacology, 2021-10)Opioid use disorder (OUD) has a variety of adverse effects on both the users and their offspring. In the current study, a random group of Sprague-Dawley rats (25 females and 15 males) were tested for intravenous ... -
Differential mechanisms of morphine antinociceptive tolerance revealed in (beta)arrestin-2 knock-out mice.
(J Neurosci, 2002-12-01)Morphine induces antinociception by activating mu opioid receptors (muORs) in spinal and supraspinal regions of the CNS. (Beta)arrestin-2 (beta)arr2), a G-protein-coupled receptor-regulating protein, regulates the muOR in ... -
Effect of ritonavir-induced cytochrome P450 3A4 inhibition on plasma fentanyl concentrations during patient-controlled epidural labor analgesia: a pharmacokinetic simulation.
(Int J Obstet Anesth, 2014-02)BACKGROUND: Ritonavir inhibition of cytochrome P450 3A4 decreases the elimination clearance of fentanyl by 67%. We used a pharmacokinetic model developed from published data to simulate the effect of sample patient-controlled ... -
Effects of nociceptin (13-17) in pain modulation at supraspinal level in mice.
(Neurosci Lett, 2002-10-11)This work was designed to observe the effects of nociceptin(13-17), one of the main metabolites of nociceptin (also termed orphanin FQ), in pain modulation at supraspinal level in mice. Intracerebroventricular (i.c.v.) ... -
Impact of Spinal Cord Stimulation on Opioid Dose Reduction: A Nationwide Analysis.
(Neurosurgery, 2020-12)<h4>Background</h4>Opioid misuse in the USA is an epidemic. Utilization of neuromodulation for refractory chronic pain may reduce opioid-related morbidity and mortality, and associated economic costs.<h4>Objective</h4>To ... -
Implementation of mandatory opioid prescribing limits in North Carolina: healthcare administrator and prescriber perspectives.
(BMC health services research, 2021-11-03)<h4>Background</h4>Recent increases in state laws to reduce opioid prescribing have demonstrated a need to understand how they are interpreted and implemented in healthcare systems. The purpose of this study was to explore ... -
Lidocaine patch for acute pain management: a meta-analysis of prospective controlled trials.
(Curr Med Res Opin, 2015-03)BACKGROUND: Local anesthetic is one of the cornerstones of multimodal analgesia. We investigated the efficacy of the lidocaine patch for acute pain management. METHODS: We searched MEDLINE, CINAHL, Scopus, and the Cochrane ... -
Measurement-based care using DSM-5 for opioid use disorder: can we make opioid medication treatment more effective?
(Addiction (Abingdon, England), 2019-08)<h4>Context and purpose</h4>Measurement-based care (MBC) is an evidence-based health-care practice in which indicators of disease are tracked to inform clinical actions, provide feedback to patients and improve outcomes. ... -
Nonmedical Opioid Pain Relievers and All-Cause Mortality: A 27-Year Follow-Up From the Epidemiologic Catchment Area Study.
(American journal of public health, 2016-03)We investigated whether nonmedical opioid pain reliever use is associated with higher mortality in the general US population.We assessed the history of nonmedical opioid pain reliever use among 9985 people interviewed at ... -
Nonopioid Treatments for Chronic Pain-Integrating Multimodal Biopsychosocial Approaches to Pain Management.
(JAMA network open, 2022-06) -
Opioid Self-Administration is Attenuated by Early-Life Experience and Gene Therapy for Anti-Inflammatory IL-10 in the Nucleus Accumbens of Male Rats.
(Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2017-10)Early-life conditions can contribute to the propensity for developing neuropsychiatric disease, including substance abuse disorders. However, the long-lasting mechanisms that shape risk or resilience for drug addiction remain ... -
Patient perspectives on community pharmacy administered and dispensing of methadone treatment for opioid use disorder: a qualitative study in the U.S.
(Addiction science & clinical practice, 2023-08)<h4>Background</h4>Pharmacy administration and dispensing of methadone treatment for opioid use disorder (PADMOUD) may address inadequate capability of opioid treatment programs (OTPs) in the US by expanding access to methadone ...
