Browsing by Subject "Analgesics, Opioid"
Now showing items 1-16 of 16
-
Associations between cigarette smoking and pain among veterans.
(Epidemiologic reviews, 2015-01-16)Individuals with chronic pain often report using cigarettes to cope, and smoking and chronic pain appear prevalent among US veterans. Pain may be a barrier to cigarette cessation and abstinence in this population. Because ... -
Buprenorphine for prescription opioid addiction in a patient with depression and alcohol dependence.
(The American journal of psychiatry, 2011-07) -
Construct and differential item functioning in the assessment of prescription opioid use disorders among American adolescents.
(Journal of the American Academy of Child and Adolescent Psychiatry, 2009-05)OBJECTIVE:To examine the psychometric properties of diagnostic criteria for prescription analgesic opioid use disorders (OUDs) and to identify background predictors of a latent continuum for OUD liability. METHOD:Data were ... -
Differential mechanisms of morphine antinociceptive tolerance revealed in (beta)arrestin-2 knock-out mice.
(J Neurosci, 2002-12-01)Morphine induces antinociception by activating mu opioid receptors (muORs) in spinal and supraspinal regions of the CNS. (Beta)arrestin-2 (beta)arr2), a G-protein-coupled receptor-regulating protein, regulates the muOR in ... -
Effect of ritonavir-induced cytochrome P450 3A4 inhibition on plasma fentanyl concentrations during patient-controlled epidural labor analgesia: a pharmacokinetic simulation.
(Int J Obstet Anesth, 2014-02)BACKGROUND: Ritonavir inhibition of cytochrome P450 3A4 decreases the elimination clearance of fentanyl by 67%. We used a pharmacokinetic model developed from published data to simulate the effect of sample patient-controlled ... -
Effects of nociceptin (13-17) in pain modulation at supraspinal level in mice.
(Neurosci Lett, 2002-10-11)This work was designed to observe the effects of nociceptin(13-17), one of the main metabolites of nociceptin (also termed orphanin FQ), in pain modulation at supraspinal level in mice. Intracerebroventricular (i.c.v.) ... -
Impact of Spinal Cord Stimulation on Opioid Dose Reduction: A Nationwide Analysis.
(Neurosurgery, 2020-12)<h4>Background</h4>Opioid misuse in the USA is an epidemic. Utilization of neuromodulation for refractory chronic pain may reduce opioid-related morbidity and mortality, and associated economic costs.<h4>Objective</h4>To ... -
Implementation of mandatory opioid prescribing limits in North Carolina: healthcare administrator and prescriber perspectives.
(BMC health services research, 2021-11-03)<h4>Background</h4>Recent increases in state laws to reduce opioid prescribing have demonstrated a need to understand how they are interpreted and implemented in healthcare systems. The purpose of this study was to explore ... -
Lidocaine patch for acute pain management: a meta-analysis of prospective controlled trials.
(Curr Med Res Opin, 2015-03)BACKGROUND: Local anesthetic is one of the cornerstones of multimodal analgesia. We investigated the efficacy of the lidocaine patch for acute pain management. METHODS: We searched MEDLINE, CINAHL, Scopus, and the Cochrane ... -
Nonmedical Opioid Pain Relievers and All-Cause Mortality: A 27-Year Follow-Up From the Epidemiologic Catchment Area Study.
(American journal of public health, 2016-03)We investigated whether nonmedical opioid pain reliever use is associated with higher mortality in the general US population.We assessed the history of nonmedical opioid pain reliever use among 9985 people interviewed at ... -
PENTAZOCINE VERSUS PENTAZOCINE WITH RECTAL DICLOFENAC FOR POSTOPERATIVE PAIN RELIEF AFTER CESAREAN SECTION- A DOUBLE BLIND RANDOMIZED PLACEBO CONTROLLED TRIAL IN A LOW RESOURCE AREA.
(Middle East J Anaesthesiol, 2016-02)BACKGROUND: The unimodal approach of using pentazocine as post-cesarean section pain relief is inadequate, hence the need for a safer, easily available and more effective multimodal approach. AIM: To evaluate the effectiveness ... -
Post-operative opioid pain management patterns for patients who receive hip surgery.
(Substance abuse treatment, prevention, and policy, 2017-03-16)Identifying optimal, post-operative opioid management strategies is a priority of health providers and government agencies. At present, there are no studies we are aware of that have formally investigated opioid prescribing ... -
Preemptive intrathecal administration of endomorphins relieves inflammatory pain in male mice via inhibition of p38 MAPK signaling and regulation of inflammatory cytokines.
(Journal of neuroinflammation, 2018-11-15)BACKGROUND:Preemptive administration of analgesic drugs reduces perceived pain and prolongs duration of antinociceptive action. Whereas several lines of evidence suggest that endomorphins, the endogenous mu-opioid agonists, ... -
Prescription pain reliever abuse and dependence among adolescents: a nationally representative study.
(Journal of the American Academy of Child and Adolescent Psychiatry, 2008-09)We examined the prevalence, patterns, and correlates of adolescents' abuse, subthreshold dependence ("diagnostic orphans"), and dependence on prescription pain relievers (PPRs) such as opioids in a representative national ... -
Reported lifetime aberrant drug-taking behaviors are predictive of current substance use and mental health problems in primary care patients.
(Pain Med, 2008-11)BACKGROUND: The aim of this report is to determine the frequency of aberrant drug behaviors and their relationship to substance abuse disorders in a large primary sample of patients receiving opioids for chronic pain. METHODS: ... -
Subtypes of nonmedical opioid users: results from the national epidemiologic survey on alcohol and related conditions.
(Drug and alcohol dependence, 2010-11)To identify subtypes of nonmedical opioid users, gender variations in psychiatric disorders, and quality of life in a representative sample of adults.Analyses of data from the 2001-2002 National Epidemiologic Survey on Alcohol ...
