Browsing by Subject "Antibody"
Now showing items 1-4 of 4
-
Bench to bedside: A Bispecific Antibody for treating Brain Tumors
(2019)Malignant gliomas are the most common primary brain tumor in adults, with an incidence of five cases per 100,000 persons per year. Grade IV glioblastoma is the most aggressive form and prognosis remains poor despite the ... -
Immunity and Autoimmunity: Host Mimicry by HIV-1
(2015)Many human monoclonal antibodies that neutralize multiple clades of HIV-1 are polyreactive and bind avidly to mammalian autoantigens. Indeed, the generation of neutralizing antibodies to the 2F5 and 4E10 epitopes of HIV-1 ... -
RNA-mediated immunotherapy regulating tumor immune microenvironment: next wave of cancer therapeutics.
(Molecular cancer, 2022-02-21)Accumulating research suggests that the tumor immune microenvironment (TIME) plays an essential role in regulation of tumor growth and metastasis. The cellular and molecular nature of the TIME influences cancer progression ... -
The Development and Mechanisms of Protective Humoral Immunity to HIV
(2018)A successful HIV-1 vaccine is likely to be comprised of a polyclonal response with multiple antiviral functions that generate both broadly neutralizing antibodies (bNAbs) that neutralize multiple strains of HIV and/ or functional ...
