Browsing by Subject "Antigens, CD27"

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A Randomized Phase II Crossover Study of Imatinib or Rituximab for Cutaneous Sclerosis after Hematopoietic Cell Transplantation.

Arai, Sally; Pidala, Joseph; Pusic, Iskra; Chai, Xiaoyu; Jaglowski, Samantha; Khera, Nandita; Palmer, Jeanne; ... (21 authors) (Clin Cancer Res, 2016-01-15)

PURPOSE: Cutaneous sclerosis occurs in 20% of patients with chronic graft-versus-host disease (GVHD) and can compromise mobility and quality of life. EXPERIMENTAL DESIGN: We conducted a prospective, multicenter, randomized, ...
CD20 deficiency in humans results in impaired T cell-independent antibody responses.

Kuijpers, Taco W; Bende, Richard J; Baars, Paul A; Grummels, Annette; Derks, Ingrid AM; Dolman, Koert M; Beaumont, Tim; ... (11 authors) (J Clin Invest, 2010-01)

CD20 was the first B cell differentiation antigen identified, and CD20-specific mAbs are commonly used for the treatment of B cell malignancies and autoantibody-mediated autoimmune diseases. Despite this the role of CD20 ...