Browsing by Subject "B-CELLS"
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Functional Relevance of Improbable Antibody Mutations for HIV Broadly Neutralizing Antibody Development. (Cell host & microbe, 2018-06)HIV-1 broadly neutralizing antibodies (bnAbs) require high levels of activation-induced cytidine deaminase (AID)-catalyzed somatic mutations for optimal neutralization potency. Probable mutations occur at sites of frequent ...