Now showing items 1-2 of 2

    • Survival Benefit of Germline BRCA Mutation is Associated with Residual Disease in Ovarian Cancer. 

      Wei, Qingyi; Shi, Tingyan; Wang, Pan; Tang, Wenbin; Jiang, Rong; Yin, Sheng; Shi, Di; ... (9 authors) (Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2018-01)
      BACKGROUND/AIMS:Prognostic value of germline BRCA1 or BRCA2 (gBRCA1/2) mutations in epithelial ovarian cancer (EOC) remains controversial, especially in the estimation of long-term survival. We previously reported the largest ...
    • Yeast screens identify the RNA polymerase II CTD and SPT5 as relevant targets of BRCA1 interaction. 

      Bennett, CB; Westmoreland, TJ; Verrier, CS; Blanchette, CA; Sabin, TL; Phatnani, HP; Mishina, YV; ... (16 authors) (PLoS One, 2008-01-16)
      BRCA1 has been implicated in numerous DNA repair pathways that maintain genome integrity, however the function responsible for its tumor suppressor activity in breast cancer remains obscure. To identify the most highly conserved ...