Browsing by Subject "Bacteria"
Now showing items 1-20 of 20
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Adjuvant Injections Altered the Ileal and Fecal Microbiota Differently with Changes in Immunoglobulin Isotypes and Antimycobacterial Antibody Responses.
(International journal of molecular sciences, 2023-02)Alterations in the gut microbiota, "dysbiosis," have been reported in autoimmune diseases, including multiple sclerosis (MS), and their animal models. Although the animal models were induced by injections of autoantigens ... -
An Experimental and Quantitative Analysis of E. coli Stress Response: Metabolic and Antibiotic Stressors
(2014)A series of experiments and mathematical models explore the response of the bacteria <italic>E. coli</italic> to stressors. Experimentally, the effect of L-homocysteine, a non-protein amino acid, is explored, and via math ... -
Bacteria localization and chorion thinning among preterm premature rupture of membranes.
(PLoS One, 2014)OBJECTIVE: Bacterial colonization of the fetal membranes and its role in pathogenesis of membrane rupture is poorly understood. Prior retrospective work revealed chorion layer thinning in preterm premature rupture of membranes ... -
Captivity humanizes the primate microbiome.
(Proc Natl Acad Sci U S A, 2018-03-01)The primate gastrointestinal tract is home to trillions of bacteria, whose composition is associated with numerous metabolic, autoimmune, and infectious human diseases. Although there is increasing evidence that modern and ... -
Cell division without FtsZ--a variety of redundant mechanisms.
(Molecular microbiology, 2010-10)Until 1998 it looked like all bacteria and archaea used a universal cytokinetic machine based on FtsZ. A dozen completely sequenced bacterial genomes all had an ftsZ gene, as did the several sequenced archaeal genomes. Then ... -
Ecological and Genomic Attributes of Novel Bacterial Taxa That Thrive in Subsurface Soil Horizons.
(mBio, 2019-10)While most bacterial and archaeal taxa living in surface soils remain undescribed, this problem is exacerbated in deeper soils, owing to the unique oligotrophic conditions found in the subsurface. Additionally, previous ... -
Ecological feedback in quorum-sensing microbial populations can induce heterogeneous production of autoinducers.
(eLife, 2017-07-25)Autoinducers are small signaling molecules that mediate intercellular communication in microbial populations and trigger coordinated gene expression via 'quorum sensing'. Elucidating the mechanisms that control autoinducer ... -
Etiology of severe non-malaria febrile illness in Northern Tanzania: a prospective cohort study.
(PLoS Negl Trop Dis, 2013)INTRODUCTION: The syndrome of fever is a commonly presenting complaint among persons seeking healthcare in low-resource areas, yet the public health community has not approached fever in a comprehensive manner. In many areas, ... -
FtsZ in bacterial cytokinesis: cytoskeleton and force generator all in one.
(Microbiology and molecular biology reviews : MMBR, 2010-12)FtsZ, a bacterial homolog of tubulin, is well established as forming the cytoskeletal framework for the cytokinetic ring. Recent work has shown that purified FtsZ, in the absence of any other division proteins, can assemble ... -
Hybrid error correction and de novo assembly of single-molecule sequencing reads.
(Nat Biotechnol, 2012-07-01)Single-molecule sequencing instruments can generate multikilobase sequences with the potential to greatly improve genome and transcriptome assembly. However, the error rates of single-molecule reads are high, which has limited ... -
IGHV1-69 B cell chronic lymphocytic leukemia antibodies cross-react with HIV-1 and hepatitis C virus antigens as well as intestinal commensal bacteria.
(PLoS One, 2014)B-cell chronic lymphocytic leukemia (B-CLL) patients expressing unmutated immunoglobulin heavy variable regions (IGHVs) use the IGHV1-69 B cell receptor (BCR) in 25% of cases. Since HIV-1 envelope gp41 antibodies also frequently ... -
Imaging of musculoskeletal bacterial infections by [124I]FIAU-PET/CT.
(PLoS One, 2007-10-10)BACKGROUND: Traditional imaging techniques for the localization and monitoring of bacterial infections, although reasonably sensitive, suffer from a lack of specificity. This is particularly true for musculoskeletal infections. ... -
Liposome division by a simple bacterial division machinery.
(Proceedings of the National Academy of Sciences of the United States of America, 2013-07)We previously reconstituted Z rings in tubular multilamellar liposomes with FtsZ-YFP-mts, where mts is a membrane-targeting amphiphilic helix. These reconstituted Z rings generated a constriction force but did not divide ... -
Microbial Phosphorus Cycling and Community Assembly in Wetland Soils and Beyond
(2010)Although microbes may strongly influence wetland phosphorus (P) cycling, specific microbial communities and P metabolic processes have not been characterized in wetlands, and microbial P cycling is poorly understood across ... -
Prospective Validation of a Rapid Host Gene Expression Test to Discriminate Bacterial From Viral Respiratory Infection.
(JAMA network open, 2022-04)<h4>Importance</h4>Bacterial and viral causes of acute respiratory illness (ARI) are difficult to clinically distinguish, resulting in the inappropriate use of antibacterial therapy. The use of a host gene expression-based ... -
Quantifying and Inhibiting Horizontal Gene Transfer-Mediated Antibiotic Resistance
(2017)Antibiotic discovery and widespread usage has revolutionized the treatment of infectious diseases. However, this golden age of modern-day medicine is threatened by the increasing prevalence of antibiotic-resistant pathogens. ... -
The Cost and Benefit of Horizontal Gene Transfer
(2022)Plasmids are key vehicles of horizontal gene transfer (HGT), mobilizing antibiotic resistance, virulence, and other traits among bacterial populations. Their fitness is directed by two orthogonal processes—vertical transfer ... -
The inoculum effect and band-pass bacterial response to periodic antibiotic treatment.
(Mol Syst Biol, 2012)The inoculum effect (IE) refers to the decreasing efficacy of an antibiotic with increasing bacterial density. It represents a unique strategy of antibiotic tolerance and it can complicate design of effective antibiotic ... -
The ocean sampling day consortium.
(Gigascience, 2015)Ocean Sampling Day was initiated by the EU-funded Micro B3 (Marine Microbial Biodiversity, Bioinformatics, Biotechnology) project to obtain a snapshot of the marine microbial biodiversity and function of the world's oceans. ... -
Validation of a Host Gene Expression Test for Bacterial/Viral Discrimination in Immunocompromised Hosts.
(Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2021-08)<h4>Background</h4>Host gene expression has emerged as a complementary strategy to pathogen detection tests for the discrimination of bacterial and viral infection. The impact of immunocompromise on host-response tests remains ...
