Browsing by Subject "Biomarker"
Now showing items 1-9 of 9
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A novel inflammatory biomarker, GlycA, associates with disease activity in rheumatoid arthritis and cardio-metabolic risk in BMI-matched controls.
(Arthritis Res Ther, 2016-04-12)BACKGROUND: RA and CVD both have inflammation as part of the underlying biology. Our objective was to explore the relationships of GlycA, a measure of glycosylated acute phase proteins, with inflammation and cardiometabolic ... -
Beyond predicting diagnosis: Is there a role for measuring biotinidase activity in liver glycogen storage diseases?
(Molecular genetics and metabolism reports, 2022-06)<h4>Introduction</h4>Biotinidase synthesis is needed to recycle biotin for essential metabolic reactions. Biotinidase activity is lower than normal levels in advanced liver disease but is higher in hepatic glycogen storage ... -
Biomarkers and proteomic analysis of osteoarthritis.
(Matrix Biol, 2014-10)Our friend and colleague, Dr. Dick Heinegård, contributed greatly to the understanding of joint tissue biochemistry, the discovery and validation of arthritis-related biomarkers and the establishment of methodology for proteomic ... -
Clinically approved combination immunotherapy: Current status, limitations, and future perspective.
(Current research in immunology, 2022-01)Immune-checkpoint inhibitor-based combination immunotherapy has become a first-line treatment for several major types of cancer including hepatocellular carcinoma (HCC), renal cell carcinoma, lung cancer, cervical cancer, ... -
Cortical Evoked Potential as a Biomarker for Deep Brain Stimulation
(2021)Deep brain stimulation (DBS) is a highly successful neuromodulation therapy for treating the motor symptoms of Parkinson’s disease (PD). However, DBS has been used for over 30 years with little change in clinically used ... -
Dynamics of biomarkers in relation to aging and mortality.
(Mech Ageing Dev, 2016-06)Contemporary longitudinal studies collect repeated measurements of biomarkers allowing one to analyze their dynamics in relation to mortality, morbidity, or other health-related outcomes. Rich and diverse data collected ... -
HPV16 antibodies as risk factors for oropharyngeal cancer and their association with tumor HPV and smoking status.
(Oral Oncol, 2015-07)BACKGROUND: Antibodies (Abs) to the HPV16 proteome increase risk for HPV-associated OPC (HPVOPC). The goal of this study was to investigate the association of a panel of HPV16 Abs with risk for OPC as well as the association ... -
In vivo cartilage strain increases following medial meniscal tear and correlates with synovial fluid matrix metalloproteinase activity
(JOURNAL OF BIOMECHANICS, 2015-06-01) -
Validation and Application of a Virtual Imaging Trial Platform for Accurate and Precise CT Quantifications in Lung Imaging
(2021)Computed Tomography (CT) is a prevalent imaging technique in modern medicine that provides physicians a non-invasive method to evaluate and diagnose various clinical conditions. To aid in diagnosis, it is important to have ...
