ALERT: This system is being upgraded on Tuesday December 12. It will not be available
for use for several hours that day while the upgrade is in progress. Deposits to DukeSpace
will be disabled on Monday December 11, so no new items are to be added to the repository
while the upgrade is in progress. Everything should be back to normal by the end of
day, December 12.
Browsing by Subject "Biomechanical Phenomena"
Now showing items 1-20 of 25
-
Bioengineered human myobundles mimic clinical responses of skeletal muscle to drugs.
(Elife, 2015-01-09)Existing in vitro models of human skeletal muscle cannot recapitulate the organization and function of native muscle, limiting their use in physiological and pharmacological studies. Here, we demonstrate engineering ... -
Biomechanical comparison of plantar-to-dorsal and dorsal-to-plantar screw fixation strength for subtalar arthrodesis.
(Einstein (Sao Paulo, Brazil), 2020-01)OBJECTIVE:To compare screw fixation strength for subtalar arthrodesis. METHODS:Eight matched pairs of cadaver feet underwent subtalar joint arthrodesis with two 7.3mm cannulated screws. Randomization was used to assign screw ... -
Biomechanics, evaluation, and management of subaxial cervical spine injuries: A comprehensive review of the literature.
(Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2021-01)<h4>Study design</h4>Literature review.<h4>Objectives</h4>It has been reported that 2.4-3.7% of all blunt trauma victims suffer some element of cervical spine fracture, with the majority of these patients suffering from ... -
Dietary inference from upper and lower molar morphology in platyrrhine primates.
(PLoS One, 2015)The correlation between diet and dental topography is of importance to paleontologists seeking to diagnose ecological adaptations in extinct taxa. Although the subject is well represented in the literature, few studies directly ... -
Energy recovery in individuals with knee osteoarthritis.
(Osteoarthritis Cartilage, 2014-06)OBJECTIVE: Pathological gaits have been shown to limit transfer between potential (PE) and kinetic (KE) energy during walking, which can increase locomotor costs. The purpose of this study was to examine whether energy exchange ... -
Evidence for an electrostatic mechanism of force generation by the bacteriophage T4 DNA packaging motor.
(Nat Commun, 2014-06-17)How viral packaging motors generate enormous forces to translocate DNA into viral capsids remains unknown. Recent structural studies of the bacteriophage T4 packaging motor have led to a proposed mechanism wherein the gp17 ... -
Functional properties of cell-seeded three-dimensionally woven poly(epsilon-caprolactone) scaffolds for cartilage tissue engineering.
(Tissue Eng Part A, 2010-04)Articular cartilage possesses complex mechanical properties that provide healthy joints the ability to bear repeated loads and maintain smooth articulating surfaces over an entire lifetime. In this study, we utilized ... -
Hand and foot pressures in the aye-aye (Daubentonia madagascariensis) reveal novel biomechanical trade-offs required for walking on gracile digits.
(J Exp Biol, 2010-05)Arboreal animals with prehensile hands must balance the complex demands of bone strength, grasping and manipulation. An informative example of this problem is that of the aye-aye (Daubentonia madagascariensis), a rare lemuriform ... -
Hip extensor mechanics and the evolution of walking and climbing capabilities in humans, apes, and fossil hominins.
(Proceedings of the National Academy of Sciences of the United States of America, 2018-04-02)The evolutionary emergence of humans' remarkably economical walking gait remains a focus of research and debate, but experimentally validated approaches linking locomotor capability to postcranial anatomy are limited. In ... -
Kinematic and dynamic gait compensations in a rat model of lumbar radiculopathy and the effects of tumor necrosis factor-alpha antagonism.
(Arthritis research & therapy, 2011-08-26)Tumor necrosis factor-α (TNFα) has received significant attention as a mediator of lumbar radiculopathy, with interest in TNF antagonism to treat radiculopathy. Prior studies have demonstrated that TNF antagonists can attenuate ... -
Kinematic and dynamic gait compensations resulting from knee instability in a rat model of osteoarthritis.
(Arthritis Res Ther, 2012-04-17)INTRODUCTION: Osteoarthritis (OA) results in pain and disability; however, preclinical OA models often focus on joint-level changes. Gait analysis is one method used to evaluate both preclinical OA models and OA patients. ... -
Locomotor head movements and semicircular canal morphology in primates.
(Proc Natl Acad Sci U S A, 2012-10-30)Animal locomotion causes head rotations, which are detected by the semicircular canals of the inner ear. Morphologic features of the canals influence rotational sensitivity, and so it is hypothesized that locomotion and ... -
Loss of cartilage structure, stiffness, and frictional properties in mice lacking PRG4.
(Arthritis Rheum, 2010-06)OBJECTIVE: To assess the role of the glycoprotein PRG4 in joint lubrication and chondroprotection by measuring friction, stiffness, surface topography, and subsurface histology of the hip joints of Prg4(-/-) and wild-type ... -
Measurement of intracellular strain on deformable substrates with texture correlation.
(J Biomech, 2007)Mechanical stimuli are important factors that regulate cell proliferation, survival, metabolism and motility in a variety of cell types. The relationship between mechanical deformation of the extracellular matrix ... -
Mechanical defenses in leaves eaten by Costa Rican howling monkeys (Alouatta palliata).
(Am J Phys Anthropol, 2006-01)Primate species often eat foods of different physical properties. This may have implications for tooth structure and wear in those species. The purpose of this study was to examine the mechanical defenses of leaves eaten ... -
Mechanobiology of the meniscus.
(J Biomech, 2015-06-01)The meniscus plays a critical biomechanical role in the knee, providing load support, joint stability, and congruity. Importantly, growing evidence indicates that the mechanobiologic response of meniscal cells plays a critical ... -
Novel Angular Measures of Cervical Deformity Account for Upper Cervical Compensation and Sagittal Alignment.
(Clinical spine surgery, 2017-08)<h4>Study design</h4>This is a retrospective review of a prospective multicenter database.<h4>Objective</h4>This study introduces 2 new cervical alignment measures accounting for both cervical deformity (CD) and upper cervical ... -
Novel animal model for Achilles tendinopathy: Controlled experimental study of serial injections of collagenase in rabbits.
(PloS one, 2018-01)Our goal was to develop a novel technique for inducing Achilles tendinopathy in animal models which more accurately represents the progressive histological and biomechanical characteristic of chronic Achilles tendinopathy ... -
Piecewise Multivariate Linearity Between Kinematic Features and Cumulative Strain Damage Measure (CSDM) Across Different Types of Head Impacts.
(Annals of biomedical engineering, 2022-11)In a previous study, we found that the relationship between brain strain and kinematic features cannot be described by a generalized linear model across different types of head impacts. In this study, we investigate if such ... -
Primary Drivers of Adult Cervical Deformity: Prevalence, Variations in Presentation, and Effect of Surgical Treatment Strategies on Early Postoperative Alignment.
(Neurosurgery, 2018-10)<h4>Background</h4>Primary drivers (PDs) of adult cervical deformity (ACD) have not been described in relation to pre- and early postoperative alignment or degree of correction.<h4>Objective</h4>To define the PDs of ACD ...
