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Browsing by Subject "Biomechanics"
Now showing items 1-20 of 43
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3D dynamic in vivo imaging of joint motion: application to measurement of anterior cruciate ligament function
(2019)More than 400,000 anterior cruciate ligament (ACL) injuries occur annually in the United States, 70% of which are non-contact. A severe consequence of ACL injury is the increased risk of early-onset of osteoarthritis (OA). ... -
A Mechanical Analysis of Suspensory Locomotion in Primates and Other Mammals
(2016)For primates, and other arboreal mammals, adopting suspensory locomotion represents one of the strategies an animal can use to prevent toppling off a thin support during arboreal movement and foraging. While numerous studies ... -
A Model of the Foot and Ankle in Running
(2011-05-11)We present several variations on a model and simulation of the foot and ankle during the course of one running stride. We summarize the motivation behind the model and similar work in the field, then describe the model and ... -
A Multi-Disciplinary Systems Approach for Modeling and Predicting Physiological Responses and Biomechanical Movement Patterns
(2017)It is currently an exciting time to be doing research at the intersection of sports and engineering. Advances in wearable sensor technology now enable large quantities of physiological and biomechanical data to be collected ... -
A Stem Cell-Based Strategy for Modeling Human Kidney Disease and Discovering Novel Therapeutics
(2022)Chronic kidney disease (CKD) is a degenerative disorder that affects millions of people worldwide and there are no targeted therapeutics. Given the global burden and increasing prevalence of CKD, the kidneys represent an ... -
Assessing the Injury Tolerance of the Human Spine
(2017)Chronic and acute back injuries are widespread, affecting people in environments where they are exposed to vibration and repeated shock. These issues have been widely reported among personnel on aircraft and small watercraft; ... -
Biomechanics of Coupled Motion in the Cervical Spine During Simulated Whiplash in Patients with Pre-existing Cervical or Lumbar Spinal Fusion: A Finite Element Study
(2014)It is well understood that loss of motion following spinal fusion increases strain in the adjacent motion segments. However, it is unclear if to date, studies on cervical spine biomechanics can be affected by the role of ... -
Biomechanics of Hierarchical Elastic Systems
(2015)Elastic energy plays important roles in biology across scales, from the molecular to organismal level, and across the tree of life. The ubiquity of elastic systems in biology is partly due to the variety of useful functions ... -
Blast-Induced Neurotrauma and the Cavitation Mechanism of Injury
(2019)Traumatic brain injuries (TBIs) are a major public health concern and socioeconomic burden worldwide. In recent years, brain injuries in US service personnel have focused attention on TBI affecting the military population ... -
Cadherin-Mediated Cell-Cell Interactions Regulates Phenotype And Morphology of Nucleus Pulposus Cells Of The Intervertebral Disc
(2015)Juvenile nucleus pulposus (NP) cells of the intervertebral disc (IVD) are large, vacuolated cells that form cell clusters with numerous cell-cell interactions. With maturation and aging, NP cells lose their ability to form ... -
Cavitation in Blunt Traumatic Brain Injury
(2021)Traumatic Brain Injury (TBI) has become a marquee injury of this generation, prevalent in both military and civilian populations (Meaney 2014). Blunt impacts to the head are the known cause of approximately 1.7 million of ... -
Computational Modeling of the Lumbar Spine: Active Musculature and Intra-abdominal Pressure in Compressive Loading
(2020)A current area of interest in lumbar injury is vertical impact loading. This includes effects of underbody blast (UBB), high speed planing boat impacts, and helicopter crashes. Lumbar spine fractures occur in 18% of all ... -
Design and Characterization of Protein-Based Building Blocks for Self-Assembled Nano-Structured Biomaterials
(2011)This study is focused on designing and characterizing protein-based building blocks in order to construct self-assembled nano-structured biomaterials. In detail, this research aims to: (1) investigate a new class of proteins ... -
Development of acoustofluidic scanning nanoscope
(2022)The largest obstacle in nanoscale microscopy is the diffraction limit. Although several means of achieving sub-diffraction resolution exist, they all have shortcomings such as cost, complexity, and processing time, which ... -
Development of Imaging-Based Models for Analyzing the Spatiotemporal Function of Intervertebral Discs
(2023)Lumbar intervertebral discs (IVD) play a critical role in facilitating the mobility and load-bearing functionality of the spine. Consequently, degeneration of the IVDs has been linked to the development of low back pain ... -
Fluid Dynamics of a Centrifugal Left Ventricular Assist Device
(2010)High shear stresses and shear rates in left ventricular assist devices (LVADs) make endothelialization of the LVAD difficult and likely contribute to cleavage of large von Willebrand factor multimers and resulting bleeding ... -
Genetic, Genomic, and Biophysical Investigations on the Robust Nature of Morphogenesis: A Study of Drosophila Dorsal Closure
(2020)Cell sheet morphogenesis is essential for metazoan development and homeostasis, contributing to key developmental stages such as neural tube closure as well as tissue maintenance through wound healing. Dorsal closure, a ... -
In vivo Mechanical Metrics for the Quantitative Assessment of Cartilage Health
(2019)Osteoarthritis (OA) is a common joint disorder, affecting over 27 million Americans. OA is characterized by the degeneration of cartilage tissue, and presents clinically with joint pain, stiffness, and limited range of motion. ... -
Influence of Outlet Boundary Conditions on Cerebrovascular Aneurysm Hemodynamics
(2016)Computational fluid dynamic (CFD) studies of blood flow in cerebrovascular aneurysms have potential to improve patient treatment planning by enabling clinicians and engineers to model patient-specific geometries and compute ... -
Injury Detection and Localization in the Spine using Acoustic Emission
(2016)The National Spinal Cord Injury Statistical Center estimates there are 12,500 new cases of spinal cord injury (SCI) in the United States every year (www.nscisc.uab.edu, 2014) and vehicular crashes are the leading cause. ...
