Browsing by Subject "Blood Glucose"
Now showing items 1-9 of 9
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Acute administration of unacylated ghrelin has no effect on Basal or stimulated insulin secretion in healthy humans.
(Diabetes, 2014-07)Unacylated ghrelin (UAG) is the predominant ghrelin isoform in the circulation. Despite its inability to activate the classical ghrelin receptor, preclinical studies suggest that UAG may promote β-cell function. We hypothesized ... -
Aprotinin improves functional outcome but not cerebral infarct size in an experimental model of stroke during cardiopulmonary bypass.
(Anesthesia and analgesia, 2010-07)<h4>Background</h4>Aprotinin, a nonspecific serine protease inhibitor, has been used to decrease bleeding and reduce the systemic inflammatory response after cardiopulmonary bypass (CPB). Studies have variably linked aprotinin ... -
Ghrelin suppresses glucose-stimulated insulin secretion and deteriorates glucose tolerance in healthy humans.
(Diabetes, 2010-09)OBJECTIVE: The orexigenic gut hormone ghrelin and its receptor are present in pancreatic islets. Although ghrelin reduces insulin secretion in rodents, its effect on insulin secretion in humans has not been established. ... -
Implant healing in experimental animal models of diabetes.
(J Diabetes Sci Technol, 2011-05-01)Diabetes mellitus is becoming increasingly prevalent worldwide. Additionally, there is an increasing number of patients receiving implantable devices such as glucose sensors and orthopedic implants. Thus, it is likely that ... -
Intake, digestibility, and passage of a commercially designed diet by two Propithecus species.
(Am J Primatol, 1999)The digestibility and passage of an experimental diet was used to compare the digestive physiology of two Propithecus species: P. verreauxi and P. tattersalli. Though both animals have a similar feeding ecology, the captive ... -
Intravital microscopy evaluation of angiogenesis and its effects on glucose sensor performance.
(J Biomed Mater Res A, 2010-06-15)An optical window model for the rodent dorsum was used to perform chronic and quantitative intravital microscopy and laser Doppler flowmetry of microvascular networks adjacent to functional and non-functional glucose sensors. ... -
Prevalence and correlates of proteinuria in Kampala, Uganda: a cross-sectional pilot study.
(BMC Res Notes, 2016-02-16)BACKGROUND: Despite the increasing prevalence of chronic kidney disease (CKD) in sub-Saharan Africa, few community-based screenings have been conducted in Uganda. Opportunities to improve the management of CKD in sub-Saharan ... -
Rationale, design, and baseline characteristics of the CArdiovascular safety and Renal Microvascular outcomE study with LINAgliptin (CARMELINA®): a randomized, double-blind, placebo-controlled clinical trial in patients with type 2 diabetes and high cardio-renal risk.
(Cardiovascular diabetology, 2018-03-14)BACKGROUND:Cardiovascular (CV) outcome trials in type 2 diabetes (T2D) have underrepresented patients with chronic kidney disease (CKD), leading to uncertainty regarding their kidney efficacy and safety. The CARMELINA® trial ... -
Safety profile of L-arginine infusion in moderately severe falciparum malaria.
(PLoS One, 2008-06-11)BACKGROUND: L-arginine infusion improves endothelial function in malaria but its safety profile has not been described in detail. We assessed clinical symptoms, hemodynamic status and biochemical parameters before and after ...
