Browsing by Subject "Blood Pressure"

Accelerated epigenetic age as a biomarker of cardiovascular sensitivity to traffic-related air pollution.

Ward-Caviness, Cavin K; Russell, Armistead G; Weaver, Anne M; Slawsky, Erik; Dhingra, Radhika; Kwee, Lydia Coulter; Jiang, Rong; ... (15 authors) (Aging, 2020-12)

<h4>Background</h4>Accelerated epigenetic age has been proposed as a biomarker of increased aging, which may indicate disruptions in cellular and organ system homeostasis and thus contribute to sensitivity to environmental ...

ACE-inhibition increases podocyte number in experimental glomerular disease independent of proliferation.

Zhang, Jiong; Yanez, David; Floege, Anna; Lichtnekert, Julia; Krofft, Ronald D; Liu, Zhi-Hong; Pippin, Jeffrey W; ... (8 authors) (Journal of the renin-angiotensin-aldosterone system : JRAAS, 2015-06)

<h4>Objective</h4>The objective of this article is to test the effects of angiotensin-converting enzyme (ACE)-inhibition on glomerular epithelial cell number in an inducible experimental model of focal segmental ...

Age trajectories of physiological indices in relation to healthy life course.

Arbeev, Konstantin G; Ukraintseva, Svetlana V; Akushevich, Igor; Kulminski, Alexander M; Arbeeva, Liubov S; Akushevich, Lucy; Culminskaya, Irina V; ... (8 authors) (Mech Ageing Dev, 2011-03)

We analysed relationship between the risk of onset of "unhealthy life" (defined as the onset of cancer, cardiovascular diseases, or diabetes) and longitudinal changes in body mass index, diastolic blood pressure, hematocrit, ...

Association between depression and hypertension using classic and revised blood pressure thresholds.

DeMoss, Dustin S; Teigen, Kari J; Claassen, Cynthia A; Fisk, Mandy J; Blair, Somer E; Bakre, Sulaimon A; Hurd, Cheryl L; ... (8 authors) (Family practice, 2020-10)

<h4>Background</h4>In a primary care population, the relationship between treatment of depression and hypertension (HTN) under the recently revised American College of Cardiology and American Heart Association HTN thresholds ...

Association of mercury exposure with blood pressure among adults near artisanal and small-scale gold mining in Madre de Dios, Peru.

Manidis, Tatiana Dorothea (2019-04-26)

There have been few studies investigating the association between mercury exposure and blood pressure, with inconsistent results. In this study, the association between hair mercury concentration with mean arterial pressure ...

Blood pressure level impacts risk of death among HIV seropositive adults in Kenya: a retrospective analysis of electronic health records.

Bloomfield, Gerald S; Hogan, Joseph W; Keter, Alfred; Holland, Thomas L; Sang, Edwin; Kimaiyo, Sylvester; Velazquez, Eric J (BMC Infect Dis, 2014-05-22)

BACKGROUND: Mortality among people with human immunodeficiency virus (HIV) infection is increasingly due to non-communicable causes. This has been observed mostly in developed countries and the routine care of HIV infected ...

Critical role of TNF-α in cerebral aneurysm formation and progression to rupture.

Starke, Robert M; Chalouhi, Nohra; Jabbour, Pascal M; Tjoumakaris, Stavropoula I; Gonzalez, L Fernando; Rosenwasser, Robert H; Wada, Kosuke; ... (12 authors) (J Neuroinflammation, 2014-04-16)

BACKGROUND: Alterations in TNF-α expression have been associated with cerebral aneurysms, but a direct role in formation, progression, and rupture has not been established. METHODS: Cerebral aneurysms were induced through ...

Decongestion strategies and renin-angiotensin-aldosterone system activation in acute heart failure.

Mentz, Robert J; Stevens, Susanna R; DeVore, Adam D; Lala, Anuradha; Vader, Justin M; AbouEzzeddine, Omar F; Khazanie, Prateeti; ... (16 authors) (JACC Heart Fail, 2015-02)

OBJECTIVES: The purpose of this study was to assess the relationship between biomarkers of renin-angiotensin-aldosterone system (RAAS) activation and decongestion strategies, worsening renal function, and clinical outcomes. ...

Effects of adult age and blood pressure on executive function and speed of processing.

Bucur, Barbara; Madden, David J (Experimental aging research, 2010-04)

Previous research has established that the effects of chronically increased blood pressure (BP) on cognition interact with adult age, but the relevant cognitive processes are not well defined. In this cross-sectional study, ...

Hair cortisol as a biomarker of stress in mindfulness training for smokers.

Goldberg, Simon B; Manley, Alison R; Smith, Stevens S; Greeson, Jeffrey M; Russell, Evan; Van Uum, Stan; Koren, Gideon; ... (8 authors) (J Altern Complement Med, 2014-08)

OBJECTIVES: Stress is a well-known predictor of smoking relapse, and cortisol is a primary biomarker of stress. The current pilot study examined changes in levels of cortisol in hair within the context of two time-intensity ...

Health and function of participants in the Long Life Family Study: A comparison with other cohorts.

Newman, Anne B; Glynn, Nancy W; Taylor, Christopher A; Sebastiani, Paola; Perls, Thomas T; Mayeux, Richard; Christensen, Kaare; ... (14 authors) (Aging (Albany NY), 2011-01)

Individuals from families recruited for the Long Life Family Study (LLFS) (n= 4559) were examined and compared to individuals from other cohorts to determine whether the recruitment targeting longevity resulted in a cohort ...

Hypertension Improvement Project (HIP): study protocol and implementation challenges.

Dolor, Rowena J; Yancy, William S; Owen, William F; Matchar, David B; Samsa, Gregory P; Pollak, Kathryn I; Lin, Pao-Hwa; ... (13 authors) (Trials, 2009-02-26)

<h4>Background</h4>Hypertension affects 29% of the adult U.S. population and is a leading cause of heart disease, stroke, and kidney failure. Despite numerous effective treatments, only 53% of people with hypertension are ...

Left ventricular dysfunction screening in hypertensive patients with N-terminal pro-B-type natriuretic peptide and electrocardiogram.

Limkakeng, Alexander T; Drake, Weiying; Mani, Giselle; Freeman, Debbie; Best, Randall; Newby, L Kristin; Chandra, Abhinav (Am J Emerg Med, 2012-01)

OBJECTIVE: Early recognition of left ventricular hypertrophy is important because antihypertensive treatment decreases morbidity and mortality. The ideal screening method for left ventricular hypertrophy in hypertensive ...

Macular Vascular Microcirculation in Eyes With Open-angle Glaucoma Using Different Visual Field Severity Classification Systems.

Bojikian, Karine D; Nobrega, Priscilla; Wen, Joanne C; Zhang, Qinqin; Mudumbai, Raghu C; Johnstone, Murray A; Wang, Ruikang K; ... (8 authors) (Journal of glaucoma, 2019-09)

<h4>Precis</h4>We found significant differences in macular vascular microcirculation between normal and glaucomatous eyes using optical coherence tomography angiography (OCTA). Macular vascular microcirculation changes also ...

Multi-objective learning and explanation for stroke risk assessment in Shanxi province.

Ma, Jing; Sun, Yiyang; Liu, Junjie; Huang, Huaxiong; Zhou, Xiaoshuang; Xu, Shixin (Scientific reports, 2022-12)

Stroke is the leading cause of death in China (Zhou et al. in The Lancet, 2019). A dataset from Shanxi Province is analyzed to predict the risk of patients at four states (low/medium/high/attack) and to estimate transition ...

Myocardial expression of a constitutively active alpha 1B-adrenergic receptor in transgenic mice induces cardiac hypertrophy.

Milano, CA; Dolber, PC; Rockman, HA; Bond, RA; Venable, ME; Allen, LF; Lefkowitz, RJ (Proc Natl Acad Sci U S A, 1994-10-11)

Transgenic mice were generated by using the alpha-myosin heavy chain promoter coupled to the coding sequence of a constitutively active mutant alpha 1B-adrenergic receptor (AR). These transgenic animals demonstrated ...

Optimizing linkage and retention to hypertension care in rural Kenya (LARK hypertension study): study protocol for a randomized controlled trial.

Vedanthan, Rajesh; Kamano, Jemima H; Naanyu, Violet; Delong, Allison K; Were, Martin C; Finkelstein, Eric A; Menya, Diana; ... (16 authors) (Trials, 2014-04-27)

BACKGROUND: Hypertension is the leading global risk factor for mortality. Hypertension treatment and control rates are low worldwide, and delays in seeking care are associated with increased mortality. Thus, a critical component ...