Browsing by Subject "Cadherins"
Now showing items 1-6 of 6
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A Functionally Conserved Gene Regulatory Network Module Governing Olfactory Neuron Diversity.
(PLoS Genet, 2016-01)Sensory neuron diversity is required for organisms to decipher complex environmental cues. In Drosophila, the olfactory environment is detected by 50 different olfactory receptor neuron (ORN) classes that are clustered in ... -
CYLD inhibits melanoma growth and progression through suppression of the JNK/AP-1 and β1-integrin signaling pathways.
(J Invest Dermatol, 2013-01)The molecular mechanisms mediating cylindromatosis (CYLD) tumor suppressor function appear to be manifold. Here, we demonstrate that, in contrast to the increased levels of phosphorylated c-Jun NH(2)-terminal kinase (pJNK), ... -
Evaluation of an epithelial plasticity biomarker panel in men with localized prostate cancer.
(Prostate Cancer Prostatic Dis, 2016-03)BACKGROUND: Given the potential importance of epithelial plasticity (EP) to cancer metastasis, we sought to investigate biomarkers related to EP in men with localized prostate cancer (PC) for the association with time to ... -
Isolation, purification and in vitro differentiation of cytotrophoblast cells from human term placenta.
(Reproductive biology and endocrinology : RB&E, 2015-07)<h4>Background</h4>The syncytialization of cytotrophoblast cells to syncytiotrophoblast is central to human placental transport and hormone production. Many techniques for in vitro study of this process have been proposed ... -
NgBR is essential for endothelial cell glycosylation and vascular development.
(EMBO Rep, 2016-02)NgBR is a transmembrane protein identified as a Nogo-B-interacting protein and recently has been shown to be a subunit required for cis-prenyltransferase (cisPTase) activity. To investigate the integrated role of NgBR in ... -
The Trim39 ubiquitin ligase inhibits APC/CCdh1-mediated degradation of the Bax activator MOAP-1.
(J Cell Biol, 2012-04-30)Proapoptotic Bcl-2 family members, such as Bax, promote release of cytochrome c from mitochondria, leading to caspase activation and cell death. It was previously reported that modulator of apoptosis protein 1 (MOAP-1), ...
