Browsing by Subject "Candida"

Now showing items 1-4 of 4

    • Breakthrough invasive fungal infections: Who is at risk? 

      Jenks, Jeffrey D; Cornely, Oliver A; Chen, Sharon C-A; Thompson, George R; Hoenigl, Martin (Mycoses, 2020-10)
      The epidemiology of invasive fungal infections (IFIs) in immunocompromised individuals has changed over the last few decades, partially due to the increased use of antifungal agents to prevent IFIs. Although this strategy ...

    • Sexual Reproduction and Signal Transduction in the Candida Species Complex 

      Reedy, Jennifer Lynne (2008-08-07)
      Although the majority of the population carries Candida spp as normal components of their microflora, these species are important human pathogens that have the ability to cause disease under conditions of immunosuppression ...

    • The impact of caspase-12 on susceptibility to candidemia. 

      Rosentul, DC; Plantinga, TS; Scott, WK; Alexander, BD; van de Geer, NMD; Perfect, JR; Kullberg, BJ; ... (9 authors) (European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 2012-03)
      Candida is one of the leading causes of sepsis, and an effective host immune response to Candida critically depends on the cytokines IL-1β and IL-18, which need caspase-1 cleavage to become bioactive. Caspase-12 has been ...

    • Tissue-Resident Macrophages in Fungal Infections. 

      Xu, Shengjie; Shinohara, Mari L (Frontiers in immunology, 2017-01)
      Invasive fungal infections result in high morbidity and mortality. Host organs targeted by fungal pathogens vary depending on the route of infection and fungal species encountered. Cryptococcus neoformans infects the respiratory ...