Browsing by Subject "Cardiac Catheterization"

Aorta-to-pulmonary vein fistula in an asymptomatic 25-year-old man.

Collier, P; Dahiya, A; Del Nido, P; Kalahasti, V; Krasuski, Richard Andrew; Stewart, WJ (Circulation, 2013-04-23)

Congenital heart disease and pulmonary hypertension.

Gupta, V; Krasuski, Richard Andrew; Tonelli, AR (Heart Fail Clin, 2012-07)

Many patients with congenital heart disease and systemic-to-pulmonary shunts develop pulmonary arterial hypertension (PAH), particularly if the cardiac defect is left unrepaired. A persistent increase in pulmonary blood ...

Effect of obesity on B-type natriuretic peptide levels in patients with pulmonary arterial hypertension.

Batal, O; Dweik, RA; Faulx, M; Hammel, JP; Hussein, AA; Khatib, OF; Krasuski, Richard Andrew; ... (8 authors) (Am J Cardiol, 2012-09-15)

Brain natriuretic peptide (BNP) levels are lower in obese patients with left ventricular failure than in their comparably ill, leaner counterparts. The effect of obesity on BNP in patients with pulmonary arterial hypertension ...

Embolization of patent foramen ovale closure devices: incidence, role of imaging in identification, potential causes, and management.

Aksoy, O; Goel, SS; Kapadia, SR; Krasuski, Richard Andrew; Tuzcu, EM (Tex Heart Inst J, 2013)

Transcatheter patent foramen ovale (PFO) closure is an alternative to antiplatelet or anticoagulative therapy in patients with cryptogenic stroke, and it is associated with a small incidence of periprocedural sequelae. Because ...

Enhancement of cardiac function after adenoviral-mediated in vivo intracoronary beta2-adrenergic receptor gene delivery.

Dolber, Paul Christian; Glower, Donald D Jr; Hata, Jonathan Andrew; Koch, Walter J; Lefkowitz, Robert J; Maurice, JP; McDonald, Patricia H; ... (10 authors) (J Clin Invest, 1999-07)

Exogenous gene delivery to alter the function of the heart is a potential novel therapeutic strategy for treatment of cardiovascular diseases such as heart failure (HF). Before gene therapy approaches to alter cardiac function ...

Gene Expression Profiles Link Respiratory Viral Infection, Platelet Response to Aspirin, and Acute Myocardial Infarction.

Cyr, Derek; Ginsburg, Geoffrey Steven; Kraus, William Erle; Lucas, Joseph E; Newby, Laura Kristin; Rose, Jason J; Voora, Deepak; ... (9 authors) (PLoS One, 2015)

BACKGROUND: Influenza infection is associated with myocardial infarction (MI), suggesting that respiratory viral infection may induce biologic pathways that contribute to MI. We tested the hypotheses that 1) a validated ...

Implementing a Continuous Quality Improvement Program in a High-Volume Clinical Echocardiography Laboratory: Improving Care for Patients With Aortic Stenosis.

Armour, A; Douglas, Pamela Susan; Harrison, JK; Horan, Seanna; Kisslo, Joseph Andrew; Minter, Stephanie; Samad, Zainab; ... (12 authors) (Circ Cardiovasc Imaging, 2016-03)

BACKGROUND: The management of aortic stenosis rests on accurate echocardiographic diagnosis. Hence, it was chosen as a test case to examine the utility of continuous quality improvement (CQI) approaches to increase ...

In vivo inhibition of elevated myocardial beta-adrenergic receptor kinase activity in hybrid transgenic mice restores normal beta-adrenergic signaling and function.

Akhter, SA; Eckhart, AD; Koch, Walter J; Lefkowitz, Robert J; Rockman, Howard A; Shotwell, K (Circulation, 1999-08-10)

BACKGROUND: The clinical syndrome of heart failure (HF) is characterized by an impaired cardiac beta-adrenergic receptor (betaAR) system, which is critical in the regulation of myocardial function. Expression of the betaAR ...

Intracoronary adenovirus-mediated delivery and overexpression of the beta(2)-adrenergic receptor in the heart : prospects for molecular ventricular assistance.

Glower, Donald D Jr; Hata, Jonathan Andrew; Koch, Walter J; Kypson, Alan P; Lefkowitz, Robert J; Lilly, R Eric; Pippen, Anne; ... (10 authors) (Circulation, 2000-02-01)

BACKGROUND: Genetic modulation of ventricular function may offer a novel therapeutic strategy for patients with congestive heart failure. Myocardial overexpression of beta(2)-adrenergic receptors (beta(2)ARs) has been shown ...

Long-term outcome and impact of surgery on adults with coronary arteries originating from the opposite coronary cusp.

Blackstone, Eugene H; Hart, Stephen A; Hobbs, Robert; Kalahasti, V; Krasuski, Richard Andrew; Lorber, R; Magyar, D; ... (8 authors) (Circulation, 2011-01-18)

BACKGROUND: An anomalous coronary artery from the opposite sinus of Valsalva may increase sudden death risk in children and young adults, and surgical intervention is often recommended. The impact of this lesion when recognized ...

Neurological injury after transcatheter aortic valve implantation: are the trees falling silently or is our hearing impaired?

Browndyke, Jeffrey Nicholas; Mathew, Joseph P (Circ Cardiovasc Interv, 2013-12)

Off-label closure during CLOSURE study.

Goel, SS; Kapadia, S; Krasuski, Richard Andrew; Prieto, L; Qureshi, AM; Stackhouse, Kathryn A; Tuzcu, EM (J Invasive Cardiol, 2012-11)

BACKGROUND: The role of percutaneous closure of patent foramen ovale (PFO) in patients with cryptogenic stroke or transient ischemic attack remains controversial. Registry data have suggested considerable benefit of closure ...

Outcomes According to Cardiac Catheterization Referral and Clopidogrel Use Among Medicare Patients With Non-ST-Segment Elevation Myocardial Infarction Discharged Without In-hospital Revascularization.

Hess, Connie Ng; Hellkamp, Anne; Roe, Matthew Todd; Thomas, Laine Elliott; Scirica, BM; Peng, SA; Peterson, Eric David; ... (8 authors) (J Am Heart Assoc, 2016-03-14)

BACKGROUND: While use of P2Y12 receptor inhibitor is recommended by guidelines, few studies have examined its effectiveness among older non-ST-segment elevation myocardial infarction patients who did not undergo coronary ...