Browsing by Subject "Chemistry, Organic"
Now showing items 1-7 of 7
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Chemical Reactions and Self-assembly in Nano-confined Environments: the Development of New Catalytic Microcontact Printing Techniques and Multicomponent Inorganic Janus Particles
(2009)Modern patterning and fabrication techniques provide powerful opportunities for the preparation of micro- and nanostructured objects with applications in fields ranging from drug delivery and bioimaging to organic based ... -
I.Total Syntheses and Biological Studies of Largazole and Brasilibactin A. II.Stereoselective Synthesis of 2,6-Cis- and 2,6-Trans-Piperidines through an Organocatalytic Aza-Michael Reaction.
(2010)The dissertation focuses on three main projects which complement the studies towards the total syntheses of biologically active natural products as well as the development of stereoselective synthesis of 2,6-disubstituted ... -
Inkless Soft Lithography: Utilizing Immobilized Enzymes and Small Molecules to Pattern Self-Assembled Monolayers Via Catalytic Microcontact Printing
(2010)During the past two decades, soft lithographic techniques that circumvent the limitations of photolithography have emerged as important tools for the transfer of patterns with sub-micron dimensions. Among these techniques, ... -
Leveraging the Reactivity of Thioesters in the Development of New Methods for Carbon–Carbon Bond Formation
(2009)Carbon–carbon bond-forming reactions comprise the most important class of synthetic transformations. The development of improved and simplified approaches to these reactions will make important and useful contributions ... -
Masked Metal Chelators of Variable Denticity to Prevent Oxidative Stress
(2010)Cellular damage due to oxidative stress is implicated in a wide variety of conditions including degenerative diseases like Alzheimer's and Parkinson's Diseases. One source of oxidative stress is the interaction of redox-active ... -
Methods for Direct Carbon-Carbon Bond Formation and Their Application to Natural Product Synthesis
(2009)Direct carbon&mdashcarbon bond formation via soft enolization and in situ enolate formation provides a straightforward approach to certain key transformations of synthetic organic chemistry. Reactions are generally operationally ... -
New Approaches To Studying Non-Covalent Molecular Interactions In Nano-Confined Environments
(2010)The goal of this work is to develop novel molecular systems, functionalization techniques, and data collection routines with which to study the binding of immobilized cognate binding partners. Our ultimate goal is the routine ...