Now showing items 1-3 of 3

    • Functional epialleles at an endogenous human centromere. 

      Ferris, A; Maloney, KA; Matheny, JE; Merrett, SL; Strome, ED; Sullivan, Beth Ann; Sullivan, LL (Proc Natl Acad Sci U S A, 2012-08-21)
      Human centromeres are defined by megabases of homogenous alpha-satellite DNA arrays that are packaged into specialized chromatin marked by the centromeric histone variant, centromeric protein A (CENP-A). Although most human ...
    • Identification and utilization of arbitrary correlations in models of recombination signal sequences. 

      Cowell, LG; Davila, M; Kelsoe, Garnett; Kepler, TB (Genome Biol, 2002)
      BACKGROUND: A significant challenge in bioinformatics is to develop methods for detecting and modeling patterns in variable DNA sequence sites, such as protein-binding sites in regulatory DNA. Current approaches sometimes ...
    • Quantification of DNA cleavage specificity in Hi-C experiments. 

      Meluzzi, D; Arya, Gaurav (Nucleic Acids Res, 2016-01-08)
      Hi-C experiments produce large numbers of DNA sequence read pairs that are typically analyzed to deduce genomewide interactions between arbitrary loci. A key step in these experiments is the cleavage of cross-linked chromatin ...