Browsing by Subject "Cocaine"
Now showing items 1-4 of 4
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Adolescent Vulnerabilities to Cocaine: Assessing Locomotor and Transcriptional Responses to Acute Cocaine and Cocaine-Induced Behavioral Plasticity During Adolescence.
(2008-05-27)Adolescence is a critical period for drug addiction in humans. Most lifelong drug addiction is initiated during adolescence and the progression from initial drug use to the expression of addictive behaviors occurs more ... -
Dopamine, Drugs, and Estradiol: The Roles of ERα and ERβ in the Mesencephalic Dopamine System and Dopamine-Mediated Behaviors of Mice
(2012)Sex differences in drug addiction are mediated in part by effects of the ovarian hormone estradiol (E2) within the ascending dopamine (DA) system from the midbrain to the striatum. Estradiol enhances the effects ... -
Enhanced rewarding properties of morphine, but not cocaine, in beta(arrestin)-2 knock-out mice.
(J Neurosci, 2003-11-12)The reinforcing and psychomotor effects of morphine involve opiate stimulation of the dopaminergic system via activation of mu-opioid receptors (muOR). Both mu-opioid and dopamine receptors are members of the G-protein-coupled ... -
Trends and correlates of cocaine use and cocaine use disorder in the United States from 2011 to 2015.
(Drug and alcohol dependence, 2017-11)BACKGROUND:Recent epidemiological data suggest a resurgence in cocaine use (CU) and cocaine-related problems in the United States. Demographic trends and correlates of problem CU are needed to determine potential factors ...
