Browsing by Subject "Cooperative Behavior"
Now showing items 1-20 of 21
-
3Rs for innovating novel antibiotics: sharing resources, risks, and rewards.
(BMJ, 2012-04-03) -
A strategy to advance the evidence base in palliative medicine: formation of a palliative care research cooperative group.
(J Palliat Med, 2010-12)BACKGROUND: Palliative medicine has made rapid progress in establishing its scientific and clinical legitimacy, yet the evidence base to support clinical practice remains deficient in both the quantity and quality of published ... -
Acquisition, Analysis, and Sharing of Data in 2015 and Beyond: A Survey of the Landscape: A Conference Report From the American Heart Association Data Summit 2015.
(J Am Heart Assoc, 2015-11-05)BACKGROUND: A 1.5-day interactive forum was convened to discuss critical issues in the acquisition, analysis, and sharing of data in the field of cardiovascular and stroke science. The discussion will serve as the foundation ... -
Application description and policy model in collaborative environment for sharing of information on epidemiological and clinical research data sets.
(PLoS One, 2010-02-19)BACKGROUND: Sharing of epidemiological and clinical data sets among researchers is poor at best, in detriment of science and community at large. The purpose of this paper is therefore to (1) describe a novel Web application ... -
Application of a rank-based genetic association test to age-at-onset data from the Collaborative Study on the Genetics of Alcoholism study.
(BMC Genet, 2005-12-30)Association studies of quantitative traits have often relied on methods in which a normal distribution of the trait is assumed. However, quantitative phenotypes from complex human diseases are often censored, highly skewed, ... -
Bumps and bridges on the road to responsible sharing of clinical trial data.
(Clin Trials, 2014-02)BACKGROUND: Sharing data from clinical trials could assist with the advancement of science and medicine, potentially providing a better understanding of both the benefits and risks of medicines and other treatments. Sharing ... -
Communication practices in physician decision-making for an unstable critically ill patient with end-stage cancer.
(J Palliat Med, 2010-08)BACKGROUND: Shared decision-making has become the standard of care for most medical treatments. However, little is known about physician communication practices in the decision making for unstable critically ill patients ... -
Development and implementation of a proficiency testing program for Luminex bead-based cytokine assays.
(J Immunol Methods, 2014-07)Luminex bead array assays are widely used for rapid biomarker quantification due to the ability to measure up to 100 unique analytes in a single well of a 96-well plate. There has been, however, no comprehensive analysis ... -
Establishing a regional, multisite database for quality improvement and service planning in community-based palliative care and hospice.
(J Palliat Med, 2010-08)BACKGROUND: Outpatient palliative care, an evolving delivery model, seeks to improve continuity of care across settings and to increase access to services in hospice and palliative medicine (HPM). It can provide a critical ... -
Establishment and maintenance of a PBMC repository for functional cellular studies in support of clinical vaccine trials.
(J Immunol Methods, 2014-07)A large repository of cryopreserved peripheral blood mononuclear cells (PBMCs) samples was created to provide laboratories testing the specimens from human immunodeficiency virus-1 (HIV-1) vaccine clinical trials the material ... -
Introduction to a Special Issue of the Journal of Immunological Methods: Building global resource programs to support HIV/AIDS clinical trial studies.
(J Immunol Methods, 2014-07)This Special Issue of the Journal of Immunological Methods includes 16 manuscripts describing quality assurance activities related to virologic and immunologic monitoring of six global laboratory resource programs that support ... -
Lack of cross-scale linkages reduces robustness of community-based fisheries management.
(PLoS One, 2009-07-16)Community-based management and the establishment of marine reserves have been advocated worldwide as means to overcome overexploitation of fisheries. Yet, researchers and managers are divided regarding the effectiveness ... -
Leukopak PBMC sample processing for preparing quality control material to support proficiency testing programs.
(J Immunol Methods, 2014-07)External proficiency testing programs designed to evaluate the performance of end-point laboratories involved in vaccine and therapeutic clinical trials form an important part of clinical trial quality assurance. Good clinical ... -
Micro-level explanations for emergent patterns of self-governance arrangements in small-scale fisheries-A modeling approach.
(PloS one, 2017-01)Small-scale fisheries (SSFs) in developing countries are expected to play a significant role in poverty alleviation and enhancing food security in the decades to come. To realize this expectation, a better understanding ... -
Mine or yours? Development of sharing in toddlers in relation to ownership understanding.
(Child Dev, 2013-05)To examine early developments in other-oriented resource sharing, fifty-one 18- and 24-month-old children were administered 6 tasks with toys or food that could be shared with an adult playmate who had none. On each task ... -
Putting together phylogenetic and ontogenetic perspectives on empathy.
(Dev Cogn Neurosci, 2012-01)The ontogeny of human empathy is better understood with reference to the evolutionary history of the social brain. Empathy has deep evolutionary, biochemical, and neurological underpinnings. Even the most advanced forms ... -
The Center for HIV/AIDS Vaccine Immunology (CHAVI) multi-site quality assurance program for cryopreserved human peripheral blood mononuclear cells.
(J Immunol Methods, 2014-07)The Center for HIV/AIDS Vaccine Immunology (CHAVI) consortium was established to determine the host and virus factors associated with HIV transmission, infection and containment of virus replication, with the goal of advancing ... -
The External Quality Assurance Oversight Laboratory (EQAPOL) proficiency program for IFN-gamma enzyme-linked immunospot (IFN-γ ELISpot) assay.
(J Immunol Methods, 2014-07)The interferon-gamma enzyme-linked immunospot (IFN-γ ELISpot) assay has been developed and used as an end-point assay in clinical trials for infectious diseases and cancer to detect the magnitude of antigen-specific immune ... -
The IGNITE network: a model for genomic medicine implementation and research.
(BMC Med Genomics, 2016-01-05)BACKGROUND: Patients, clinicians, researchers and payers are seeking to understand the value of using genomic information (as reflected by genotyping, sequencing, family history or other data) to inform clinical decision-making. ... -
The Psychiatric Genomics Consortium Posttraumatic Stress Disorder Workgroup: Posttraumatic Stress Disorder Enters the Age of Large-Scale Genomic Collaboration.
(Neuropsychopharmacology, 2015-09)The development of posttraumatic stress disorder (PTSD) is influenced by genetic factors. Although there have been some replicated candidates, the identification of risk variants for PTSD has lagged behind genetic research ...