Browsing by Subject "DIPG"
Now showing items 1-3 of 3
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Pre-Clinical Models of Diffuse Intrinsic Pontine Glioma.
(Front Oncol, 2015)Diffuse intrinsic pontine glioma (DIPG) is a rare and incurable brain tumor that arises in the brainstem of children predominantly between the ages of 6 and 8. Its intricate morphology and involvement of normal pons tissue ... -
Regional Differences in Glioma: The Role of Pax3 in the Mechanisms and Cellular Origins of Brainstem Glioma
(2014)Brain tumors are an incredibly diverse group of neoplasms, as evidenced by their varied locations in the brain, histological characteristics, and genetic alterations. Brain tumor heterogeneity can be potentially explained ... -
The role of H3.3K27M-induced gene repression in brainstem gliomagenesis
(2017)Diffuse Intrinsic Pontine Glioma (DIPG) is a highly aggressive pediatric brainstem tumor recently found to contain high incidence of H3.3K27M mutations. These mutations reprogram the H3K27me3 epigenetic landscape of DIPG ...
