Now showing items 1-6 of 6

    • Cannabinoid exposure and altered DNA methylation in rat and human sperm. 

      Kollins, Scott; Murphy, Susan; Price, Thomas; Raburn, Douglas; Mitchell, John; McClernon, Joseph; Huang, zhiqing; ... (18 authors) (Epigenetics, 2018-01)
      Little is known about the reproductive effects of paternal cannabis exposure. We evaluated associations between cannabis or tetrahydrocannabinol (THC) exposure and altered DNA methylation in sperm from humans and ...
    • DNA methylation age is associated with mortality in a longitudinal Danish twin study. 

      Aviv, A; Christensen, Kaare; Christiansen, L; Lenart, A; McGue, M; Tan, Q; Vaupel, James Walton (Aging Cell, 2016-02)
      An epigenetic profile defining the DNA methylation age (DNAm age) of an individual has been suggested to be a biomarker of aging, and thus possibly providing a tool for assessment of health and mortality. In this study, ...
    • Efficient analysis of complex, multimodal genomic data 

      Acharya, Chaitanya Ramanuj (2016)
      Our primary goal is to better understand complex diseases using statistically disciplined approaches. As multi-modal data is streaming out of consortium projects like Genotype-Tissue Expression (GTEx) project, which aims ...
    • Evolution and Mechanisms of Plasticity in Wild Baboons (Papio cynocephalus) 

      Lea, Amanda Jeanne (2017)
      In many species, early life experiences have striking effects on health, reproduction, and survival in adulthood. Thus, early life conditions shape a range of evolutionarily relevant traits, and in doing so alter ...
    • Genomic Insights Into the Lichen Symbiosis: <italic>Cladonia grayi</italic> as a Model Lichen 

      McDonald, Tami (2011)
      Lichens are symbioses between a fungus and a photosynthesizing partner such as a green alga or a cyanobacterium. Unlike mycorrhizal or rhizobial symbioses, the lichen symbiosis is not well understood either morphologically ...
    • Predicting Genome-wide DNA Methylation in Humans 

      Zhang, Weiwei (2014)
      DNA methylation is one of the most studied and important epigenetic modifications in cells, playing a role in DNA transcription, splicing, and imprinting. Recently, advanced genome-wide DNA methylation profiling technologies ...