Browsing by Subject "DNA methylation"
Now showing items 1-11 of 11
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Cannabinoid exposure and altered DNA methylation in rat and human sperm.
(Epigenetics, 2018-01)Little is known about the reproductive effects of paternal cannabis exposure. We evaluated associations between cannabis or tetrahydrocannabinol (THC) exposure and altered DNA methylation in sperm from humans and ... -
Cannabis use and the sperm epigenome: a budding concern?
(Environmental epigenetics, 2020-01)The United States is swiftly moving toward increased legalization of medical and recreational cannabis. Currently considered the most commonly used illicit psychoactive drug, recreational cannabis is legal in 11 states and ... -
DNA methylation age is associated with mortality in a longitudinal Danish twin study.
(Aging Cell, 2016-02)An epigenetic profile defining the DNA methylation age (DNAm age) of an individual has been suggested to be a biomarker of aging, and thus possibly providing a tool for assessment of health and mortality. In this study, ... -
Efficient analysis of complex, multimodal genomic data
(2016)Our primary goal is to better understand complex diseases using statistically disciplined approaches. As multi-modal data is streaming out of consortium projects like Genotype-Tissue Expression (GTEx) project, which aims ... -
Evolution and Mechanisms of Plasticity in Wild Baboons (Papio cynocephalus)
(2017)In many species, early life experiences have striking effects on health, reproduction, and survival in adulthood. Thus, early life conditions shape a range of evolutionarily relevant traits, and in doing so alter ... -
Evolution of Gene Regulation in Papio Baboons
(2019)Changes in gene regulation are thought to play an important role in primate evolution and divergence. In support of this hypothesis, comparative evidence clearly demonstrate that gene expression patterns differ between closely ... -
Genomic Insights Into the Lichen Symbiosis: <italic>Cladonia grayi</italic> as a Model Lichen
(2011)Lichens are symbioses between a fungus and a photosynthesizing partner such as a green alga or a cyanobacterium. Unlike mycorrhizal or rhizobial symbioses, the lichen symbiosis is not well understood either morphologically ... -
Predicting Genome-wide DNA Methylation in Humans
(2014)DNA methylation is one of the most studied and important epigenetic modifications in cells, playing a role in DNA transcription, splicing, and imprinting. Recently, advanced genome-wide DNA methylation profiling technologies ... -
Quantification of the pace of biological aging in humans through a blood test, the DunedinPoAm DNA methylation algorithm.
(eLife, 2020-05-05)Biological aging is the gradual, progressive decline in system integrity that occurs with advancing chronological age, causing morbidity and disability. Measurements of the pace of aging are needed as surrogate endpoints ... -
The Balance of Parental Effects and Within Generation Plasticity: The Role of Parent and Offspring DNA Methylation on Response to Cues of Neighbor Presence
(2021)While phenotypic plasticity has been widely documented, the relative contribution of parent versus offspring environment to determining progeny phenotypes and the persistence of parental effects throughout progeny development ... -
The Epigenetic and Neurodevelopmental Consequences of Maternal Tobacco Smoke Exposure
(2019)Maternal smoking is a deleterious and preventable risk to fetal health. Maternal tobacco smoke (TS) exposure in humans has been linked to impaired fetal growth, preterm birth, sudden infant death syndrome, and neurobehavioral ...
