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Browsing by Subject "DNA replication"
Now showing items 1-4 of 4
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Chromatin Dynamics and Regulation of the Helicase During Replication Initiation
(2021)DNA replication is an intricate process within eukaryotic cells that must be precisely executed to preserve genetic information. This process begins at multiple start sites, or origins of replication, along each chromosome ... -
Defining the Role of the Histone Methyltransferase, PR-Set7, in Maintaining the Genome Integrity of Drosophila Melanogaster
(2016)The complete and faithful duplication of the genome is essential to ensure normal cell division and organismal development. Eukaryotic DNA replication is initiated at multiple sites termed origins of replication that are ... -
Genome-Wide Dynamics of Chromatin Maturation Following DNA Replication
(2018)All DNA-templated events, including replication and gene transcription, occur in the context of the local chromatin environment. The passage of the replication machinery results in disassembly of chromatin, which must be ... -
The Biochemical Characterization of Drosophila melanogaster RecQ4 Helicase
(2011)RecQ4, a member of the conserved RecQ family of helicases, is involved in replication and associated with several clinical syndromes. Although biologically important, the biochemistry of RecQ4 has remained elusive. We have ...
