Browsing by Subject "Databases, Protein"

Bayesian inference for genomic data integration reduces misclassification rate in predicting protein-protein interactions.

Xing, Chuanhua; Dunson, David B (PLoS Comput Biol, 2011-07)

Protein-protein interactions (PPIs) are essential to most fundamental cellular processes. There has been increasing interest in reconstructing PPIs networks. However, several critical difficulties exist in obtaining reliable ...

DOMINE: a comprehensive collection of known and predicted domain-domain interactions.

Yellaboina, Sailu; Tasneem, Asba; Zaykin, Dmitri V; Raghavachari, Balaji; Jothi, Raja (Nucleic acids research, 2011-01)

DOMINE is a comprehensive collection of known and predicted domain-domain interactions (DDIs) compiled from 15 different sources. The updated DOMINE includes 2285 new domain-domain interactions (DDIs) inferred from experimentally ...

Statistical analysis of crystallization database links protein physico-chemical features with crystallization mechanisms.

Fusco, Diana; Barnum, Timothy J; Bruno, Andrew E; Luft, Joseph R; Snell, Edward H; Mukherjee, Sayan; Charbonneau, Patrick (PLoS One, 2014)

X-ray crystallography is the predominant method for obtaining atomic-scale information about biological macromolecules. Despite the success of the technique, obtaining well diffracting crystals still critically limits going ...