Browsing by Subject "Deep Brain Stimulation"
Now showing items 1-9 of 9
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Chronic spinal cord electrical stimulation protects against 6-hydroxydopamine lesions.
(Scientific reports, 2014-01-23)Although L-dopa continues to be the gold standard for treating motor symptoms of Parkinson's disease (PD), it presents long-term complications. Deep brain stimulation is effective, but only a small percentage of idiopathic ... -
Computational Analysis of Clinical Brain Sub-cortical Structures from Ultrahigh-Field MRI
(2015)Volumetric segmentation of brain sub-cortical structures within the basal ganglia and thalamus from Magnetic Resonance Image (MRI) is necessary for non-invasive diagnosis and neurosurgery planning. This is a challenging ... -
Creating and parameterizing patient-specific deep brain stimulation pathway-activation models using the hyperdirect pathway as an example.
(PloS one, 2017-01)<h4>Background</h4>Deep brain stimulation (DBS) is an established clinical therapy and computational models have played an important role in advancing the technology. Patient-specific DBS models are now common tools in both ... -
Design and in vivo evaluation of more efficient and selective deep brain stimulation electrodes.
(Journal of neural engineering, 2015-08)<h4>Objective</h4>Deep brain stimulation (DBS) is an effective treatment for movement disorders and a promising therapy for treating epilepsy and psychiatric disorders. Despite its clinical success, the efficiency and selectivity ... -
Evaluation of high-perimeter electrode designs for deep brain stimulation.
(Journal of neural engineering, 2014-08)<h4>Objective</h4>Deep brain stimulation (DBS) is an effective treatment for movement disorders and a promising therapy for treating epilepsy and psychiatric disorders. Despite its clinical success, complications including ... -
Influences of interpolation error, electrode geometry, and the electrode-tissue interface on models of electric fields produced by deep brain stimulation.
(IEEE transactions on bio-medical engineering, 2014-02)Deep brain stimulation (DBS) is an established therapy for movement disorders, but the fundamental mechanisms by which DBS has its effects remain unknown. Computational models can provide insights into the mechanisms of ... -
Stimulation Efficiency With Decaying Exponential Waveforms in a Wirelessly Powered Switched-Capacitor Discharge Stimulation System.
(IEEE transactions on bio-medical engineering, 2018-05)The purpose of this study was to test the feasibility of using a switched-capacitor discharge stimulation (SCDS) system for electrical stimulation, and, subsequently, determine the overall energy saved compared to a conventional ... -
StimVision v2: Examples and Applications in Subthalamic Deep Brain Stimulation for Parkinson's Disease.
(Neuromodulation : journal of the International Neuromodulation Society, 2021-02)<h4>Objective</h4>Subthalamic deep brain stimulation (DBS) is an established therapy for Parkinson's disease. Connectomic DBS modeling is a burgeoning subfield of research aimed at characterizing the axonal connections activated ... -
The assessment of resistance to antidepressant treatment: Rationale for the Antidepressant Treatment History Form: Short Form (ATHF-SF).
(Journal of psychiatric research, 2019-06)There is considerable diversity in how treatment-resistant depression (TRD) is defined. However, every definition incorporates the concept that patients with TRD have not benefited sufficiently from one or more adequate ...
