Browsing by Subject "Diffusion Tensor Imaging"
Now showing items 1-20 of 22
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A case of frontal neuropsychological and neuroimaging signs following multiple primary-blast exposure.
(Neurocase, 2012-06)Blast-related traumatic brain injury (TBI) from the Afghanistan and Iraq wars represents a significant medical concern for troops and veterans. To better understand the consequences of primary-blast injury in humans, we ... -
Accelerating Brain DTI and GYN MRI Studies Using Neural Network
(2021)There always exists a demand to accelerate the time-consuming MRI acquisition process. Many methods have been proposed to achieve this goal, including deep learning method which appears to be a robust tool compared ... -
Adult age differences in functional connectivity during executive control.
(Neuroimage, 2010-08-15)Task switching requires executive control processes that undergo age-related decline. Previous neuroimaging studies have identified age-related differences in brain activation associated with global switching effects (dual-task ... -
Altered diffusion tensor imaging measurements in aged transgenic Huntington disease rats.
(Brain Struct Funct, 2013-05)Rodent models of Huntington disease (HD) are valuable tools for investigating HD pathophysiology and evaluating new therapeutic approaches. Non-invasive characterization of HD-related phenotype changes is important for monitoring ... -
Brain connectivity and visual attention.
(Brain connectivity, 2013-01)Emerging hypotheses suggest that efficient cognitive functioning requires the integration of separate, but interconnected cortical networks in the brain. Although task-related measures of brain activity suggest ... -
Brain structural connectivity increases concurrent with functional improvement: evidence from diffusion tensor MRI in children with cerebral palsy during therapy.
(NeuroImage. Clinical, 2015-01-09)Cerebral Palsy (CP) refers to a heterogeneous group of permanent but non-progressive movement disorders caused by injury to the developing fetal or infant brain (Bax et al., 2005). Because of its serious long-term consequences, ... -
Characterization of subtle brain abnormalities in a mouse model of Hedgehog pathway antagonist-induced cleft lip and palate.
(PLoS One, 2014)Subtle behavioral and cognitive deficits have been documented in patient cohorts with orofacial clefts (OFCs). Recent neuroimaging studies argue that these traits are associated with structural brain abnormalities but have ... -
Cocaine dependence does not contribute substantially to white matter abnormalities in HIV infection.
(Journal of neurovirology, 2017-06)This study investigated the association of HIV infection and cocaine dependence with cerebral white matter integrity using diffusion tensor imaging (DTI). One hundred thirty-five participants stratified by HIV and cocaine ... -
Correction for Eddy Current-Induced Echo-Shifting Effect in Partial-Fourier Diffusion Tensor Imaging.
(Biomed Res Int, 2015)In most diffusion tensor imaging (DTI) studies, images are acquired with either a partial-Fourier or a parallel partial-Fourier echo-planar imaging (EPI) sequence, in order to shorten the echo time and increase ... -
Cross-hemispheric collaboration and segregation associated with task difficulty as revealed by structural and functional connectivity.
(J Neurosci, 2015-05-27)Although it is known that brain regions in one hemisphere may interact very closely with their corresponding contralateral regions (collaboration) or operate relatively independent of them (segregation), the specific brain ... -
Diffusion Tensor Imaging Biomarkers of Stem Cell Therapy Efficacy in Pediatric Cerebral Palsy
(2012)Cerebral palsy (CP) is a non-progressive sensory-motor disorder and is one of the most costly and debilitating chronic pediatric conditions, affecting 2-3 out of 1000 children in the United States. To better understand the ... -
Diffusion tensor imaging of cerebral white matter integrity in cognitive aging.
(Biochimica et biophysica acta, 2012-03)In this article we review recent research on diffusion tensor imaging (DTI) of white matter (WM) integrity and the implications for age-related differences in cognition. Neurobiological mechanisms defined from DTI analyses ... -
Disconnected aging: cerebral white matter integrity and age-related differences in cognition.
(Neuroscience, 2014-09)Cognition arises as a result of coordinated processing among distributed brain regions and disruptions to communication within these neural networks can result in cognitive dysfunction. Cortical disconnection may thus contribute ... -
Effects of chronic mild traumatic brain injury on white matter integrity in Iraq and Afghanistan war veterans.
(Human Brain Mapping, 2013-11)Mild traumatic brain injury (TBI) is a common source of morbidity from the wars in Iraq and Afghanistan. With no overt lesions on structural MRI, diagnosis of chronic mild TBI in military veterans relies on obtaining an ... -
Gender-specific structural abnormalities in major depressive disorder revealed by fixel-based analysis.
(NeuroImage. Clinical, 2019-01-08)<h4>Background</h4>Major depressive disorder (MDD) is a chronic disease with a large global impact. There are currently no clinically useful predictors of treatment outcome, and the development of biomarkers to inform clinical ... -
Global versus tract-specific components of cerebral white matter integrity: relation to adult age and perceptual-motor speed.
(Brain structure & function, 2015-09)Although age-related differences in white matter have been well documented, the degree to which regional, tract-specific effects can be distinguished from global, brain-general effects is not yet clear. Similarly, the manner ... -
Improved delineation of short cortical association fibers and gray/white matter boundary using whole-brain three-dimensional diffusion tensor imaging at submillimeter spatial resolution.
(Brain Connect, 2014-11)Recent emergence of human connectome imaging has led to a high demand on angular and spatial resolutions for diffusion magnetic resonance imaging (MRI). While there have been significant growths in high angular resolution ... -
Less wiring, more firing: low-performing older adults compensate for impaired white matter with greater neural activity.
(Cereb Cortex, 2015-04)The reliable neuroimaging finding that older adults often show greater activity (over-recruitment) than younger adults is typically attributed to compensation. Yet, the neural mechanisms of over-recruitment in older adults ... -
Quantitative mapping of trimethyltin injury in the rat brain using magnetic resonance histology.
(Neurotoxicology, 2014-05)The growing exposure to chemicals in our environment and the increasing concern over their impact on health have elevated the need for new methods for surveying the detrimental effects of these compounds. Today's gold standard ... -
Sources of disconnection in neurocognitive aging: cerebral white-matter integrity, resting-state functional connectivity, and white-matter hyperintensity volume.
(Neurobiol Aging, 2017-06)Age-related decline in fluid cognition can be characterized as a disconnection among specific brain structures, leading to a decline in functional efficiency. The potential sources of disconnection, however, are unclear. ...
