Now showing items 1-9 of 9

    • Characterization of a canine model of glycogen storage disease type IIIa. 

      Yi, Haiqing; Thurberg, Beth L; Curtis, Sarah; Austin, Stephanie; Fyfe, John; Koeberl, Dwight D; Kishnani, Priya S; ... (8 authors) (Dis Model Mech, 2012-11)
      Glycogen storage disease type IIIa (GSD IIIa) is an autosomal recessive disease caused by deficiency of glycogen debranching enzyme (GDE) in liver and muscle. The disorder is clinically heterogeneous and progressive, and ...
    • Citizen Science as a New Tool in Dog Cognition Research. 

      Stewart, Laughlin; MacLean, Evan L; Ivy, David; Woods, Vanessa; Cohen, Eliot; Rodriguez, Kerri; McIntyre, Matthew; ... (13 authors) (PLoS One, 2015)
      Family dogs and dog owners offer a potentially powerful way to conduct citizen science to answer questions about animal behavior that are difficult to answer with more conventional approaches. Here we evaluate the quality ...
    • Contrast in intracardiac acoustic radiation force impulse images of radiofrequency ablation lesions. 

      Eyerly, Stephanie A; Bahnson, Tristram D; Koontz, Jason I; Bradway, David P; Dumont, Douglas M; Trahey, Gregg E; Wolf, Patrick D (Ultrason Imaging, 2014-04)
      We have previously shown that intracardiac acoustic radiation force impulse (ARFI) imaging visualizes tissue stiffness changes caused by radiofrequency ablation (RFA). The objectives of this in vivo study were to (1) quantify ...
    • Correction of glycogen storage disease type III with rapamycin in a canine model. 

      Yi, Haiqing; Brooks, Elizabeth D; Thurberg, Beth L; Fyfe, John C; Kishnani, Priya S; Sun, Baodong (J Mol Med (Berl), 2014-06)
      UNLABELLED: Recently, we reported that progression of liver fibrosis and skeletal myopathy caused by extensive accumulation of cytoplasmic glycogen at advanced age is the major feature of a canine model of glycogen storage ...
    • Intracardiac acoustic radiation force impulse imaging: a novel imaging method for intraprocedural evaluation of radiofrequency ablation lesions. 

      Eyerly, Stephanie A; Bahnson, Tristram D; Koontz, Jason I; Bradway, David P; Dumont, Douglas M; Trahey, Gregg E; Wolf, Patrick D (Heart Rhythm, 2012-11)
      BACKGROUND: Arrhythmia recurrence after cardiac radiofrequency ablation (RFA) for atrial fibrillation has been linked to conduction through discontinuous lesion lines. Intraprocedural visualization and corrective ablation ...
    • Natural Progression of Canine Glycogen Storage Disease Type IIIa. 

      Brooks, Elizabeth D; Yi, Haiqing; Austin, Stephanie L; Thurberg, Beth L; Young, Sarah P; Fyfe, John C; Kishnani, Priya S; ... (8 authors) (Comp Med, 2016-02)
      Glycogen storage disease type IIIa (GSD IIIa) is caused by a deficiency of glycogen debranching enzyme activity. Hepatomegaly, muscle degeneration, and hypoglycemia occur in human patients at an early age. Long-term complications ...
    • Pathogenesis of growth failure and partial reversal with gene therapy in murine and canine Glycogen Storage Disease type Ia. 

      Arumugam, Ramamani; Brooks, ED; Curtis, S; Demaster, A; Freemark, Michael Scott; Jackson, MW; Kishnani, Priya Sunil; ... (11 authors) (Mol Genet Metab, 2013-06)
      Glycogen Storage Disease type Ia (GSD-Ia) in humans frequently causes delayed bone maturation, decrease in final adult height, and decreased growth velocity. This study evaluates the pathogenesis of growth failure and the ...
    • Relationship of T2-Weighted MRI Myocardial Hyperintensity and the Ischemic Area-At-Risk. 

      Kim, Han W; Van Assche, Lowie; Jennings, Robert B; Wince, W Benjamin; Jensen, Christoph J; Rehwald, Wolfgang G; Wendell, David C; ... (16 authors) (Circ Res, 2015-07-17)
      RATIONALE: After acute myocardial infarction (MI), delineating the area-at-risk (AAR) is crucial for measuring how much, if any, ischemic myocardium has been salvaged. T2-weighted MRI is promoted as an excellent method to ...
    • Transmission of MRSA between companion animals and infected human patients presenting to outpatient medical care facilities. 

      Ferreira, Jorge Pinto; Anderson, Kevin L; Correa, Maria T; Lyman, Roberta; Ruffin, Felicia; Reller, L Barth; Fowler, Vance G (PLoS One, 2011)
      Methicillin-resistant Staphylococcus aureus (MRSA) is a significant pathogen in both human and veterinary medicine. The importance of companion animals as reservoirs of human infections is currently unknown. The companion ...