Browsing by Subject "Dopamine"
Now showing items 1-20 of 21
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Activation in mesolimbic and visuospatial neural circuits elicited by smoking cues: evidence from functional magnetic resonance imaging.
(Am J Psychiatry, 2002-06)OBJECTIVE: The authors sought to increase understanding of the brain mechanisms involved in cigarette addiction by identifying neural substrates modulated by visual smoking cues in nicotine-deprived smokers. METHOD: Event-related ... -
Activity in descending dopaminergic neurons represents but is not required for leg movements in the fruit fly Drosophila.
(Physiol Rep, 2015-03)Modulatory descending neurons (DNs) that link the brain to body motor circuits, including dopaminergic DNs (DA-DNs), are thought to contribute to the flexible control of behavior. Dopamine elicits locomotor-like outputs ... -
Cognitive Neurostimulation: Learning to Volitionally Invigorate Mesolimbic Reward Network Activation
(2015)The brain’s dopaminergic system is critical to adaptive behaviors, and is centrally implicated in various pathologies. For decades, research has aimed at better characterizing what drives the mesolimbic dopamine system and ... -
Cooperativity between the Phosphorylation of Thr(95) and Ser(77) of NHERF-1 in the Hormonal Regulation of Renal Phosphate Transport
(JOURNAL OF THE ROYAL SOCIETY INTERFACE, 2013-01-06)The phosphorylation of the sodium-hydrogen exchanger regulatory factor-1 (NHERF-1) plays a key role in the regulation of renal phosphate transport by parathyroid hormone (PTH) and dopamine. Ser(77) in the first PDZ domain ... -
Dopamine regulation of human speech and bird song: a critical review.
(Brain Lang, 2012-09)To understand the neural basis of human speech control, extensive research has been done using a variety of methodologies in a range of experimental models. Nevertheless, several critical questions about learned vocal motor ... -
Dopamine, Drugs, and Estradiol: The Roles of ERα and ERβ in the Mesencephalic Dopamine System and Dopamine-Mediated Behaviors of Mice
(2012)Sex differences in drug addiction are mediated in part by effects of the ovarian hormone estradiol (E2) within the ascending dopamine (DA) system from the midbrain to the striatum. Estradiol enhances the effects ... -
Dopaminergic modulation of retinal processing from starlight to sunlight.
(Journal of pharmacological sciences, 2019-05-04)Neuromodulators such as dopamine, enable context-dependent plasticity of neural circuit function throughout the central nervous system. For example, in the retina, dopamine tunes visual processing for daylight and nightlight ... -
Emotional Modulation of Time Perception
(2014)Our perception of time is not veridical but rather is consistently modulating by changing dynamics in our environment. Anecdotal experiences suggest that emotions can be powerful modulators of time perception; nevertheless, ... -
Enhanced rewarding properties of morphine, but not cocaine, in beta(arrestin)-2 knock-out mice.
(J Neurosci, 2003-11-12)The reinforcing and psychomotor effects of morphine involve opiate stimulation of the dopaminergic system via activation of mu-opioid receptors (muOR). Both mu-opioid and dopamine receptors are members of the G-protein-coupled ... -
Functional Selectivity at the Dopamine D2 Receptor
(2015)The neuromodulator dopamine signals through the dopamine D2 receptor (D2R) to modulate central nervous system functions through diverse signal transduction pathways. D2R is a prominent target for drug treatments in disorders ... -
Increased renal dopamine and acute renal adaptation to a high-phosphate diet.
(American journal of physiology. Renal physiology, 2011-05)The current experiments explore the role of dopamine in facilitating the acute increase in renal phosphate excretion in response to a high-phosphate diet. Compared with a low-phosphate (0.1%) diet for 24 h, mice ... -
Paternal Cannabis Exposure Prior to Mating, but Not Δ9-Tetrahydrocannabinol, Elicits Deficits in Dopaminergic Synaptic Activity in the Offspring.
(Toxicological sciences : an official journal of the Society of Toxicology, 2021-09-30)The legalization and increasing availability of cannabis products raises concerns about the impact on offspring of users, and little has appeared on the potential contribution of paternal use. We administered cannabis extract ... -
Role of the midbrain dopaminergic system in modulation of vocal brain activation by social context.
(Eur J Neurosci, 2007-06)In a well-studied model of social behaviour, male zebra finches sing directed song to court females and undirected song, used possibly for practice or advertisement. Although the two song types are similar, the level of ... -
Social context-dependent singing-regulated dopamine.
(J Neurosci, 2006-08-30)Like the mammalian striatum, the songbird striatum receives dense dopaminergic input from the midbrain ventral tegmental area-substantia nigra pars compacta complex. The songbird striatum also contains a unique vocal nucleus, ... -
Socioeconomic Stress by Dopamine Receptor 2 Gene Interactions in the Development of Obesity
(2013)Background: Previous research suggests that early life socioeconomic stress and certain genetic polymorphisms may be partly associated with increased adiposity; however, research on both genetic and environmental predictors ... -
Succinylated octopamine ascarosides and a new pathway of biogenic amine metabolism in Caenorhabditis elegans.
(J Biol Chem, 2013-06-28)The ascarosides, small-molecule signals derived from combinatorial assembly of primary metabolism-derived building blocks, play a central role in Caenorhabditis elegans biology and regulate many aspects of development and ... -
The dopamine metabolite 3-methoxytyramine is a neuromodulator.
(PLoS One, 2010-10-18)Dopamine (3-hydroxytyramine) is a well-known catecholamine neurotransmitter involved in multiple physiological functions including movement control. Here we report that the major extracellular metabolite of dopamine, ... -
The Pan social brain: An evolutionary history of neurochemical receptor genes and their potential impact on sociocognitive differences.
(Journal of human evolution, 2021-02-09)Humans have unique cognitive capacities that, compared with apes, are not only simply expressed as a higher level of general intelligence, but also as a quantitative difference in sociocognitive skills. Humans' closest living ... -
The role of dopamine in operant learning
(2020)In order to ensure survival, animals must learn to repeat actions that produce beneficial outcomes. When an action leads to a desired outcome, animals learn to associate the action with the outcome. These associations can ... -
The Role of Dopaminergic Systems in the Neurobehavioral Teratology of Organophosphates in Zebrafish
(2016)Background: Organophosphate (OP) pesticides are well-known developmental neurotoxicants that have been linked to abnormal cognitive and behavioral endpoints through both epidemiological studies and animal models of behavioral ...
