Browsing by Subject "Down Syndrome"

Now showing items 1-5 of 5

    • Outcome of transplantation for acute lymphoblastic leukemia in children with Down syndrome. 

      Hitzler, Johann K; He, Wensheng; Doyle, John; Cairo, Mitchell; Camitta, Bruce M; Chan, Ka Wah; Diaz Perez, Miguel A; ... (21 authors) (Pediatric blood & cancer, 2014-06)
      We report on 27 patients with Down syndrome (DS) and acute lymphoblastic leukemia (ALL) who received allogeneic hematopoietic cell transplantation (HCT) between 2000 and 2009. Seventy-eight percent of patients received ...

    • Outcome of transplantation for acute myelogenous leukemia in children with Down syndrome. 

      Hitzler, Johann K; He, Wensheng; Doyle, John; Cairo, Mitchell; Camitta, Bruce M; Chan, Ka Wah; Diaz Perez, Miguel A; ... (21 authors) (Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2013-06)
      Data on outcomes of allogeneic transplantation in children with Down syndrome and acute myelogenous leukemia (DS-AML) are scarce and conflicting. Early reports stress treatment-related mortality as the main barrier; a recent ...

    • Resource Needs, Availability and Use Amongst Children with Down Syndrome and their Caregivers in Galle, Sri Lanka 

      Logan, Dilani (2018)
      Background: Down Syndrome (DS) is the most commonly identified aneuploidy amongst children in Sri Lanka, with a prevalence of 76.3%. This study intended to determine the level of disability of children with DS aged 5-12, ...

    • Safety and efficacy of rivastigmine in adolescents with Down syndrome: long-term follow-up. 

      Heller, James H; Spiridigliozzi, Gail A; Crissman, Blythe G; McKillop, Jane Anne; Yamamoto, Haru; Kishnani, Priya S (J Child Adolesc Psychopharmacol, 2010-12)
      Following the completion of a 20-week, open-label study of the safety and efficacy of liquid rivastigmine for adolescents with Down syndrome, 5 of the 10 adolescents in the clinical trial continued long-term rivastigmine ...

    • Sleep Disorders in Childhood Neurogenetic Disorders 

      Dosier, Laura; Vaughn, Bradley; Fan, Zheng (Children, 2017-09-12)
      Genetic advances in the past three decades have transformed our understanding and treatment of many human diseases including neurogenetic disorders. Most neurogenetic disorders can be classified as "rare disease," ...