Now showing items 1-6 of 6

    • Constraint and trade-offs regulate energy expenditure during childhood. 

      Urlacher, Samuel S; Snodgrass, J Josh; Dugas, Lara R; Sugiyama, Lawrence S; Liebert, Melissa A; Joyce, Cara J; Pontzer, Herman (Science advances, 2019-12-18)
      Children's metabolic energy expenditure is central to evolutionary and epidemiological frameworks for understanding variation in human phenotype and health. Nonetheless, the impact of a physically active lifestyle and heavy ...
    • Energy recovery in individuals with knee osteoarthritis. 

      Sparling, TL; Schmitt, D; Miller, CE; Guilak, F; Somers, TJ; Keefe, FJ; Queen, RM (Osteoarthritis Cartilage, 2014-06)
      OBJECTIVE: Pathological gaits have been shown to limit transfer between potential (PE) and kinetic (KE) energy during walking, which can increase locomotor costs. The purpose of this study was to examine whether energy exchange ...
    • Metabolic programming and PDHK1 control CD4+ T cell subsets and inflammation. 

      Gerriets, Valerie A; Kishton, Rigel J; Nichols, Amanda G; Macintyre, Andrew N; Inoue, Makoto; Ilkayeva, Olga; Winter, Peter S; ... (22 authors) (J Clin Invest, 2015-01)
      Activation of CD4+ T cells results in rapid proliferation and differentiation into effector and regulatory subsets. CD4+ effector T cell (Teff) (Th1 and Th17) and Treg subsets are metabolically distinct, yet the specific ...
    • Persistent hypermetabolism and longitudinal energy expenditure in critically ill patients with COVID-19. 

      Whittle, John; Molinger, Jeroen; MacLeod, David; Haines, Krista; Wischmeyer, Paul E; LEEP-COVID Study Group (Critical care (London, England), 2020-09-28)
    • Skeletal muscle mitochondrial fragmentation and impaired bioenergetics from nutrient overload are prevented by carbon monoxide. 

      Gasier, Heath G; Dohl, Jacob; Suliman, Hagir B; Piantadosi, Claude A; Yu, Tianzheng (American journal of physiology. Cell physiology, 2020-10)
      Nutrient excess increases skeletal muscle oxidant production and mitochondrial fragmentation that may result in impaired mitochondrial function, a hallmark of skeletal muscle insulin resistance. This led us to explore whether ...
    • Whole body mechanics of stealthy walking in cats. 

      Bishop, Kristin L; Pai, Anita K; Schmitt, Daniel (PLoS One, 2008)
      The metabolic cost associated with locomotion represents a significant part of an animal's metabolic energy budget. Therefore understanding the ways in which animals manage the energy required for locomotion by controlling ...