Browsing by Subject "Epistasis"
Now showing items 1-3 of 3
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Bayesian Kernel Models for Statistical Genetics and Cancer Genomics
(2017)The main contribution of this thesis is to examine the utility of kernel regression ap- proaches and variance component models for solving complex problems in statistical genetics and molecular biology. Many of these types ... -
Characterization of Gene Interaction and Assessment of Ld Matrix Measures for the Analysis of Biological Pathway Association
(2009)Leukotrienes are arachidonic acid derivatives long known for their inflammatory properties and their involvement with a number of human diseases, most notably asthma. Recently, leukotriene-based inflammation has also been ... -
Puzzling role of genetic risk factors in human longevity: "risk alleles" as pro-longevity variants.
(Biogerontology, 2016-02)Complex diseases are major contributors to human mortality in old age. Paradoxically, many genetic variants that have been associated with increased risks of such diseases are found in genomes of long-lived people, and do ...
