Browsing by Subject "Evidence-Based Medicine"
Now showing items 1-20 of 23
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A few of our favorite unconfirmed ideas.
(Crit Care, 2015)Medical practice is rooted in our dependence on the best available evidence from incremental scientific experimentation and rigorous clinical trials. Progress toward determining the true worth of ongoing practice or suggested ... -
A strategy to advance the evidence base in palliative medicine: formation of a palliative care research cooperative group.
(J Palliat Med, 2010-12)BACKGROUND: Palliative medicine has made rapid progress in establishing its scientific and clinical legitimacy, yet the evidence base to support clinical practice remains deficient in both the quantity and quality of published ... -
An Update on Surgical versus Expectant Management of Ovarian Endometriomas in Infertile Women.
(BioMed research international, 2015-01)Ovarian endometriomas are a common manifestation of endometriosis that can represent a more severe stage of the disease. There is much debate over the treatment of these cysts in infertile women, particularly before use ... -
Assessing applicability when comparing medical interventions: AHRQ and the Effective Health Care Program.
(Journal of clinical epidemiology, 2011-11)<h4>Objective</h4>To describe a systematic approach for identifying, reporting, and synthesizing information to allow consistent and transparent consideration of the applicability of the evidence in a systematic review according ... -
Caveat emptor: the combined effects of multiplicity and selective reporting.
(Trials, 2018-09-17)Clinical trials and systematic reviews of clinical trials inform healthcare decisions. There is growing concern, however, about results from clinical trials that cannot be reproduced. Reasons for nonreproducibility include ... -
Chapter 11: challenges in and principles for conducting systematic reviews of genetic tests used as predictive indicators.
(Journal of general internal medicine, 2012-06)In this paper, we discuss common challenges in and principles for conducting systematic reviews of genetic tests. The types of genetic tests discussed are those used to 1). determine risk or susceptibility in asymptomatic ... -
Chapter 1: Introduction to the Methods Guide for Medical Test Reviews.
(Journal of general internal medicine, 2012-06)Evaluation of medical tests presents challenges distinct from those involved in the evaluation of therapies; in particular, the very great importance of context and the dearth of comprehensive RCTs aimed at comparing the ... -
Chapter 5: assessing risk of bias as a domain of quality in medical test studies.
(Journal of general internal medicine, 2012-06)Assessing methodological quality is a necessary activity for any systematic review, including those evaluating the evidence for studies of medical test performance. Judging the overall quality of an individual study involves ... -
Chapter 6: assessing applicability of medical test studies in systematic reviews.
(Journal of general internal medicine, 2012-06)Use of medical tests should be guided by research evidence about the accuracy and utility of those tests in clinical care settings. Systematic reviews of the literature about medical tests must address applicability to real-world ... -
Chapter 7: grading a body of evidence on diagnostic tests.
(Journal of general internal medicine, 2012-06)<h4>Introduction</h4>Grading the strength of a body of diagnostic test evidence involves challenges over and above those related to grading the evidence from health care intervention studies. This chapter identifies challenges ... -
Critical Review of Current Approaches for Echocardiographic Reproducibility and Reliability Assessment in Clinical Research.
(Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography, 2016-12)<h4>Background</h4>There is no broadly accepted standard method for assessing the quality of echocardiographic measurements in clinical research reports, despite the recognized importance of this information in assessing ... -
Developing Treatment Guidelines During a Pandemic Health Crisis: Lessons Learned From COVID-19.
(Annals of internal medicine, 2021-08)The development of the National Institutes of Health (NIH) COVID-19 Treatment Guidelines began in March 2020 in response to a request from the White House Coronavirus Task Force. Within 4 days of the request, the NIH COVID-19 ... -
Effect of a Multifaceted Quality Improvement Intervention on Hospital Personnel Adherence to Performance Measures in Patients With Acute Ischemic Stroke in China: A Randomized Clinical Trial.
(JAMA, 2018-07)In China and other parts of the world, hospital personnel adherence to evidence-based stroke care is limited.To determine whether a multifaceted quality improvement intervention can improve hospital personnel adherence to ... -
Effective Implementation of Enhanced Recovery Pathway Programs: The Key to Disseminating Evidence into Practice.
(Jt Comm J Qual Patient Saf, 2015-10) -
Evidence-based Assessment of Current and Emerging Bladder-sparing Therapies for Non-muscle-invasive Bladder Cancer After Bacillus Calmette-Guerin Therapy: A Systematic Review and Meta-analysis.
(European urology oncology, 2020-06)<h4>Context</h4>Currently, there is no standard of care for patients with non-muscle-invasive bladder cancer (NMIBC) who recur despite bacillus Calmette-Guerin (BCG) therapy. Although radical cystectomy is recommended, many ... -
GxE interactions between FOXO genotypes and drinking tea are significantly associated with prevention of cognitive decline in advanced age in China.
(J Gerontol A Biol Sci Med Sci, 2015-04)Logistic regression analysis based on data from 822 Han Chinese oldest old aged 92+ demonstrated that interactions between carrying FOXO1A-266 or FOXO3-310 or FOXO3-292 and tea drinking at around age 60 or at present time ... -
Intravenous starches: is suspension the best solution?
(Anesth Analg, 2014-09) -
Making Clinical Practice Guidelines Pragmatic: How Big Data and Real World Evidence Can Close the Gap.
(Annals of the Academy of Medicine, Singapore, 2018-12)Clinical practice guidelines (CPGs) have become ubiquitous in every field of medicine today but there has been limited success in implementation and improvement in health outcomes. Guidelines are largely based on the results ... -
Measurement-based care using DSM-5 for opioid use disorder: can we make opioid medication treatment more effective?
(Addiction (Abingdon, England), 2019-08)<h4>Context and purpose</h4>Measurement-based care (MBC) is an evidence-based health-care practice in which indicators of disease are tracked to inform clinical actions, provide feedback to patients and improve outcomes. ... -
Pre-discharge prognostic factors of physical function among older adults with hip fracture surgery: a systematic review.
(Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2019-05)<h4>Introduction</h4>To identify, organize, and assess the evidence level of pre-discharge prognostic factors of physical function beyond discharge after hip fracture surgery.<h4>Methods</h4>We performed a systematic search ...
