Browsing by Subject "Extracellular Matrix Proteins"
Now showing items 1-7 of 7
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Astrocytes refine cortical connectivity at dendritic spines.
(Elife, 2014-12-17)During cortical synaptic development, thalamic axons must establish synaptic connections despite the presence of the more abundant intracortical projections. How thalamocortical synapses are formed and maintained in this ... -
Baseline Visual Field Findings in the RUSH2A Study: Associated Factors and Correlation With Other Measures of Disease Severity.
(American journal of ophthalmology, 2020-11)<h4>Purpose</h4>To report baseline visual fields in the Rate of Progression in USH2A-related Retinal Degeneration (RUSH2A) study.<h4>Design</h4>Cross-sectional study within a natural history study.<h4>Methods</h4>Setting: ... -
Chondrogenesis of adult stem cells from adipose tissue and bone marrow: induction by growth factors and cartilage-derived matrix.
(Tissue Eng Part A, 2010-02)OBJECTIVES: Adipose-derived stem cells (ASCs) and bone marrow-derived mesenchymal stem cells (MSCs) are multipotent adult stem cells with potential for use in cartilage tissue engineering. We hypothesized that these cells ... -
Elucidating the Molecular Composition of Cartilage by Proteomics.
(J Proteome Res, 2016-02-05)Articular cartilage consists of chondrocytes and two major components, a collagen-rich framework and highly abundant proteoglycans. Most prior studies defining the zonal distribution of cartilage have extracted proteins ... -
Integrin-mediated interactions with extracellular matrix proteins for nucleus pulposus cells of the human intervertebral disc.
(J Orthop Res, 2013-10)The extracellular matrix (ECM) of the human intervertebral disc is rich in molecules that interact with cells through integrin-mediated attachments. Porcine nucleus pulposus (NP) cells have been shown to interact with laminin ... -
Interleukin-13 induces collagen type-1 expression through matrix metalloproteinase-2 and transforming growth factor-β1 in airway fibroblasts in asthma.
(The European respiratory journal, 2014-02)Airway remodelling is a feature of asthma that contributes to loss of lung function. One of the central components of airway remodelling is subepithelial fibrosis. Interleukin (IL)-13 is a key T-helper 2 cytokine and is ... -
Thousands of human mobile element fragments undergo strong purifying selection near developmental genes.
(Proceedings of the National Academy of Sciences of the United States of America, 2007-05)At least 5% of the human genome predating the mammalian radiation is thought to have evolved under purifying selection, yet protein-coding and related untranslated exons occupy at most 2% of the genome. Thus, the majority ...
