Browsing by Subject "Fas Ligand Protein"
Now showing items 1-3 of 3
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Apoptotic variants as predictors of risk of oropharyngeal cancer recurrence after definitive radiotherapy.
(Int J Cancer, 2015-11-15)Single nucleotide polymorphisms (SNPs) in the promoter region of FAS and FASLG may alter their transcriptional activity. Thus, we determined the associations between four FAS and FASLG promoter variants (FAS1377G>A, rs2234767; ... -
Site disparities in apoptotic variants as predictors of risk for second primary malignancy in patients with squamous cell carcinoma of the head and neck.
(BMC cancer, 2016-02-08)FAS/FASL promoter variants are considered in altering transcriptional activity of those genes and consequently alter regulation of cell death. However, no studies have investigated whether tumor sites contribute ... -
The cytolytic molecules Fas ligand and TRAIL are required for murine thymic graft-versus-host disease.
(J Clin Invest, 2010-01)Thymic graft-versus-host disease (tGVHD) can contribute to profound T cell deficiency and repertoire restriction after allogeneic BM transplantation (allo-BMT). However, the cellular mechanisms of tGVHD and interactions ...
