Now showing items 1-3 of 3

    • Characterization of topographical effects on macrophage behavior in a foreign body response model. 

      Chen, S; Jones, JA; Xu, Y; Low, H-Y; Anderson, JM; Leong, KW (Biomaterials, 2010-05)
      Current strategies to limit macrophage adhesion, fusion and fibrous capsule formation in the foreign body response have focused on modulating material surface properties. We hypothesize that topography close to biological ...
    • The effect of nitric oxide surface flux on the foreign body response to subcutaneous implants. 

      Brown, NL; Klitzman, Bruce; Koh, A; Nichols, Scott P; Riccio, DA; Rose, MB; Schoenfisch, MH; ... (9 authors) (Biomaterials, 2012-09)
      Although the release of nitric oxide (NO) from biomaterials has been shown to reduce the foreign body response (FBR), the optimal NO release kinetics and doses remain unknown. Herein, polyurethane-coated wire substrates ...
    • Tissue-Integrating Oxygen Sensors: Continuous Tracking of Tissue Hypoxia. 

      Klitzman, Bruce; Wisniewski, Natalie A; Nichols, Scott P; Gamsey, Soya J; Pullins, Steve; Au-Yeung, Kit Y; Helton, Kristen L (Advances in experimental medicine and biology, 2017-01)
      We describe a simple method of tracking oxygen in real-time with injectable, tissue-integrating microsensors. The sensors are small (500 μm × 500 μm × 5 mm), soft, flexible, tissue-like, biocompatible hydrogel s that have ...