Browsing by Subject "G protein"
Now showing items 1-3 of 3
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Functional Selectivity at the Dopamine D2 Receptor
(2015)The neuromodulator dopamine signals through the dopamine D2 receptor (D2R) to modulate central nervous system functions through diverse signal transduction pathways. D2R is a prominent target for drug treatments in disorders ... -
Identifying Molecular Mechanisms of beta-arrestin Biased G Protein-Coupled Receptor Signaling
(2017)G protein-coupled receptors (GPCRs) represent the largest and the most versatile family of cell surface receptors. Members of this receptor family translate diverse extracellular cues to intracellular responses, and are ... -
The Functional and Pathophysiological Consequences of Transducin γ-Subunit Knockout
(2019)The initial steps of vertebrate vision take place in the retina, where light-sensitive rod and cone photoreceptor cells translate light into an electrical signal through a biochemical process called phototransduction. Transducin, ...
