Browsing by Subject "GENE"
Now showing items 1-4 of 4
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Comparison of the molecular properties of retinitis pigmentosa P23H and N15S amino acid replacements in rhodopsin.
(PloS one, 2019-01)Mutations in the RHO gene encoding for the visual pigment protein, rhodopsin, are among the most common cause of autosomal dominant retinitis pigmentosa (ADRP). Previous studies of ADRP mutations in different domains of ... -
Macrophage cells secrete factors including LRP1 that orchestrate the rejuvenation of bone repair in mice.
(Nature communications, 2018-12-05)The pace of repair declines with age and, while exposure to a young circulation can rejuvenate fracture repair, the cell types and factors responsible for rejuvenation are unknown. Here we report that young macrophage cells ... -
Microgravity induces proteomics changes involved in endoplasmic reticulum stress and mitochondrial protection.
(Scientific reports, 2016-09-27)On Earth, biological systems have evolved in response to environmental stressors, interactions dictated by physical forces that include gravity. The absence of gravity is an extreme stressor and the impact of its absence ... -
The utility of nuclear gapCp in resolving polyploid fern origins
(Systematic Botany, 2008-10-01)Although polyploidy is rampant in ferns and plays a major role in shaping their diversity, the evolutionary history of many polyploid species remains poorly understood. Nuclear DNA sequences can provide valuable information ...