Now showing items 1-4 of 4

    • Captivity humanizes the primate microbiome. 

      Clayton, Jonathan B; Vangay, Pajau; Huang, Hu; Ward, Tonya; Hillmann, Benjamin M; Al-Ghalith, Gabriel A; Travis, Dominic A; ... (17 authors) (Proc Natl Acad Sci U S A, 2018-03-01)
      The primate gastrointestinal tract is home to trillions of bacteria, whose composition is associated with numerous metabolic, autoimmune, and infectious human diseases. Although there is increasing evidence that modern and ...
    • Postnatally-transmitted HIV-1 Envelope variants have similar neutralization-sensitivity and function to that of nontransmitted breast milk variants. 

      Fouda, Genevieve G; Mahlokozera, Tatenda; Salazar-Gonzalez, Jesus F; Salazar, Maria G; Learn, Gerald; Kumar, Surender B; Dennison, S Moses; ... (26 authors) (Retrovirology, 2013-01-10)
      BACKGROUND: Breastfeeding is a leading cause of infant HIV-1 infection in the developing world, yet only a minority of infants exposed to HIV-1 via breastfeeding become infected. As a genetic bottleneck severely restricts ...
    • Stem Cell-Derived Models of Viral Infections in the Gastrointestinal Tract. 

      Lanik, Wyatt E; Mara, Madison A; Mihi, Belgacem; Coyne, Carolyn B; Good, Misty (Viruses, 2018-03-10)
      Studies on the intestinal epithelial response to viral infection have previously been limited by the absence of in vitro human intestinal models that recapitulate the multicellular complexity of the gastrointestinal tract. ...
    • Type III Interferons in Antiviral Defenses at Barrier Surfaces. 

      Wells, Alexandra I; Coyne, Carolyn B (Trends in immunology, 2018-10)
      Barrier surfaces such as the epithelium lining the respiratory and gastrointestinal (GI) tracts, the endothelium comprising the blood-brain barrier (BBB), and placental trophoblasts provide key physical and immunological ...