Browsing by Subject "Health"
Now showing items 1-20 of 35
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A high-resolution map of human evolutionary constraint using 29 mammals.
(Nature, 2011-10-12)The comparison of related genomes has emerged as a powerful lens for genome interpretation. Here we report the sequencing and comparative analysis of 29 eutherian genomes. We confirm that at least 5.5% of the human genome ... -
Acute administration of unacylated ghrelin has no effect on Basal or stimulated insulin secretion in healthy humans.
(Diabetes, 2014-07)Unacylated ghrelin (UAG) is the predominant ghrelin isoform in the circulation. Despite its inability to activate the classical ghrelin receptor, preclinical studies suggest that UAG may promote β-cell function. We hypothesized ... -
Aging and health--a systems biology perspective. Introduction.
(Interdiscip Top Gerontol, 2015) -
An Assessment of Health Outcomes Among Orphans in the Positive Outcomes for Orphans Study in Rural Settings of Kenya and Tanzania
(2011)<bold>Objectives</bold>: To compare measures of health and health quality between Orphans and Vulnerable Children (OVC) in different living arrangements-- institutional and community care; and to correlate different measures ... -
Architectures of Aliveness: Building Beyond Gravity
(2015)In the context of today's global mobility, information, bodies and goods are circulating across the globe, and even further into outer space. However, we face a paradox: the more we move, the more we become sedentary. The ... -
Beta2-adrenergic receptor gene polymorphisms as systemic determinants of healthy aging in an evolutionary context.
(Mech Ageing Dev, 2010-05)The Gln(27)Glu polymorphism but not the Arg(16)Gly polymorphism of the beta2-adrenergic receptor (ADRB2) gene appears to be associated with a broad range of aging-associated phenotypes, including cancers at different sites, ... -
Clean Cookstoves and Health in Samlout, Cambodia
(2016)This paper discusses results from a study of the use of cleaner cooking solutions and general health status of people in rural areas from the Battambang province of Cambodia. Data collection included 372 demographic, health ... -
Dealing with Racism: Black Middle-Class Health in the 21st Century
(2018)There is widespread evidence that health disparities between whites and blacks in the U.S. cannot be fully explained by inter-group socioeconomic differences. Further, research shows that racism plays a significant role ... -
Diferencias y disparidades de salud para la comunidad hispana en Durham
(2020-04-01)Due to multiple factors including language and culture, predominantly Hispanic neighborhoods in Durham County may experience health differently than other areas in the county. In conjunction with the Durham County Department ... -
Epigenetics: A Paradigm Shift or Tweaking the Details?
(2015-05-12)*Designated as an Exemplary Master's Project for 2014-15* We know that our lifestyle choices and experiences can influence our health: the food we eat, the environment we live in, and the social relationships we form can ... -
Essays in Applied Microeconomics
(2013)The essays in applied microeconomics contained within this dissertation examine prices in the developing economy contexts of Indonesia and the Philippines. Prices, observed and unobserved, are determined by and incentivize ... -
Examination of Health Care Transition, Health Status, and Functional Outcomes Among Adolescents and Young Adults with Intellectual Disability
(2020)Adolescence is a period marked by tremendous social, emotional and physical changes; however, adolescents and young adults (AYAs) with intellectual disability (ID), who must navigate this period with limitations in intellectual ... -
Foreign Aid Allocation and Impact: A Sub-National Analysis of Malawi
(2013-04-15)This project estimates the first sub-national model of foreign aid allocation and impact. Newly geocoded aid project data from Malawi is used in combination with multiple rounds of living standards data to predict the allocation ... -
Genes, Race, and Causation: US Public Perspectives About Racial Difference
(Race and Social Problems, 2018-06-01)© 2018, Springer Science+Business Media, LLC, part of Springer Nature. Concerns have been raised that the increase in popular interest in genetics may herald a new era within which racial inequities are seen as “natural” ... -
Improving Birth Outcomes in North Carolina
(2021-04-16)Birth outcomes for children are the foundational building block for life after birth. Adverse birth outcomes influence a child’s development immediately after birth, and their health outcomes throughout their lives. Health ... -
Incorporating Comparative Effectiveness Research Results into the U.S. Medicare Program
(2010-12)Comparative Effectiveness Research (CER) is a method of evaluation that compares the effectiveness of two or more medical treatments by assessing comparative health outcomes. Historically, there has been a lack of implementation ... -
Managing the Nitrogen Cascade: Analysis of the International Management of Reactive Nitrogen
(2006)Reactive nitrogen (Nr) plays a role in numerous environmental and human health concerns, including climate change, eutrophication, acid rain, respiratory illness and cancer. While produced naturally, increased human creation ... -
Measuring The Effects of Mining on Peru's Public Health: Is The Apurimac Region Prepared To Assess Heavy Metal Exposure?
(2016-04-27)Peru’s Ministry of Health has approached Duke University because it seeks help with evaluating whether heavy metals exposure (in mining regions) is associated with adverse health outcomes. To aid in this effort, I have ... -
Measuring the Impact of the Medicare Prescription Drug, Improvement, and Modernization Act of 2003 on Shortages of Sterile Injectable Oncology Drugs
(2012-04-26)The problem of U.S. pharmaceutical drug shortages is one that has steadily grown in severity over the course of the past decade, particularly in the years since 2006. Some types of drugs have proven to be more susceptible ...
