Browsing by Subject "Heart Defects, Congenital"
Now showing items 1-11 of 11
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A Multifaceted Approach to Pulmonary Hypertension in Adults With Congenital Heart Disease.
(Progress in cardiovascular diseases, 2018-09)Advances in the management of congenital heart disease (CHD) in children have resulted in growing numbers of adults with CHD. Pulmonary arterial hypertension related to CHD (PAH-CHD) is a common complication, affecting up ... -
Adult Congenital Heart Disease Care Provision: the Need for a Jack/Jackie of All Trades.
(Progress in cardiovascular diseases, 2018-09) -
Congenital heart disease and pulmonary hypertension.
(Heart Fail Clin, 2012-07)Many patients with congenital heart disease and systemic-to-pulmonary shunts develop pulmonary arterial hypertension (PAH), particularly if the cardiac defect is left unrepaired. A persistent increase in pulmonary blood ... -
Congenital Heart Disease Epidemiology in the United States: Blindly Feeling for the Charging Elephant.
(Circulation, 2016-07-12) -
Coronary Disease and Modifying Cardiovascular Risk in Adult Congenital Heart Disease Patients: Should General Guidelines Apply?
(Progress in cardiovascular diseases, 2018-09)There are >1.4 million adult congenital heart disease (CHD; ACHD) patients living in the United States. Coronary artery disease (CAD) is at least as prevalent in ACHD patients as in the general population and has become ... -
Development of the morpholino gene knockdown technique in Fundulus heteroclitus: a tool for studying molecular mechanisms in an established environmental model.
(Aquat Toxicol, 2008-05-30)A significant challenge in environmental toxicology is that many genetic and genomic tools available in laboratory models are not developed for commonly used environmental models. The Atlantic killifish (Fundulus heteroclitus) ... -
Developmental exposure to a complex PAH mixture causes persistent behavioral effects in naive Fundulus heteroclitus (killifish) but not in a population of PAH-adapted killifish.
(Neurotoxicol Teratol, 2016-01)Acute exposures to some individual polycyclic aromatic hydrocarbons (PAHs) and complex PAH mixtures are known to cause cardiac malformations and edema in the developing fish embryo. However, the heart is not the only organ ... -
Essential role of beta-adrenergic receptor kinase 1 in cardiac development and function.
(Proc Natl Acad Sci U S A, 1996-11-12)The beta-adrenergic receptor kinase 1 (beta ARK1) is a member of the G protein-coupled receptor kinase (GRK) family that mediates the agonist-dependent phosphorylation and desensitization of G protein-coupled receptors. ... -
Long Term Consequences of the Fontan Procedure and How to Manage Them.
(Progress in cardiovascular diseases, 2018-09-17)In 1971, Fontan and Baudet described a surgical technique for successful palliation of patients with tricuspid atresia. Subsequently, this technique has been applied to treat most forms of functional single ventricles and ... -
Neurological injury after transcatheter aortic valve implantation: are the trees falling silently or is our hearing impaired?
(Circ Cardiovasc Interv, 2013-12) -
Transcatheter Valve Replacement for Right-sided Valve Disease in Congenital Heart Patients.
(Progress in cardiovascular diseases, 2018-09-17)Pulmonary and/or tricuspid valve dysfunction is common among individuals with congenital heart disease, and surgical intervention often carries prohibitive risks. Transcatheter valve replacement (TVR) of the right-sided ...
