Browsing by Subject "Heart Diseases"
Now showing items 1-20 of 20
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Emerging roles of junctophilin-2 in the heart and implications for cardiac diseases.
(Cardiovascular research, 2014-07)Cardiomyocytes rely on a highly specialized subcellular architecture to maintain normal cardiac function. In a little over a decade, junctophilin-2 (JPH2) has become recognized as a cardiac structural protein critical in ... -
Executive summary: heart disease and stroke statistics--2012 update: a report from the American Heart Association.
(Circulation, 2012-01)Each year, the American Heart Association (AHA), in conjunction with the Centers for Disease Control and Prevention, the National Institutes of Health, and other government agencies, brings together the most up-to-date statistics ... -
Executive summary: heart disease and stroke statistics--2013 update: a report from the American Heart Association.
(Circulation, 2013-01)Each year, the American Heart Association (AHA), in conjunction with the Centers for Disease Control and Prevention, the National Institutes of Health, and other government agencies, brings together the most up-to-date statistics ... -
Executive summary: heart disease and stroke statistics--2014 update: a report from the American Heart Association.
(Circulation, 2014-01)Each year, the American Heart Association (AHA), in conjunction with the Centers for Disease Control and Prevention, the National Institutes of Health, and other government agencies, brings together the most up-to-date statistics ... -
Exosome and Biomimetic Nanoparticle Therapies for Cardiac Regenerative Medicine.
(Current stem cell research & therapy, 2020-01)Exosomes and biomimetic nanoparticles have great potential to develop into a wide-scale therapeutic platform within the regenerative medicine industry. Exosomes, a subgroup of EVs with diameter ranging from 30-100 nm, have ... -
Heart disease and stroke statistics--2011 update: a report from the American Heart Association.
(Circulation, 2011-02)Each year, the American Heart Association (AHA), in conjunction with the Centers for Disease Control and Prevention, the National Institutes of Health, and other government agencies, brings together the most up-to-date statistics ... -
Heart disease and stroke statistics--2012 update: a report from the American Heart Association.
(Circulation, 2012-01)Each year, the American Heart Association (AHA), in conjunction with the Centers for Disease Control and Prevention, the National Institutes of Health, and other government agencies, brings together the most up-to-date statistics ... -
Heart disease and stroke statistics--2013 update: a report from the American Heart Association.
(Circulation, 2013-01)Each year, the American Heart Association (AHA), in conjunction with the Centers for Disease Control and Prevention, the National Institutes of Health, and other government agencies, brings together the most up-to-date statistics ... -
Heart disease and stroke statistics--2014 update: a report from the American Heart Association.
(Circulation, 2014-01)Each year, the American Heart Association (AHA), in conjunction with the Centers for Disease Control and Prevention, the National Institutes of Health, and other government agencies, brings together the most up-to-date statistics ... -
Heart disease and stroke statistics--2015 update: a report from the American Heart Association.
(Circulation, 2015-01)Each year, the American Heart Association (AHA), in conjunction with the Centers for Disease Control and Prevention, the National Institutes of Health, and other government agencies, brings together the most up-to-date statistics ... -
Heart Disease and Stroke Statistics-2018 Update: A Report From the American Heart Association.
(Circulation, 2018-03)Each year, the American Heart Association (AHA), in conjunction with the Centers for Disease Control and Prevention, the National Institutes of Health, and other government agencies, brings together in a single document ... -
High-sensitivity troponin assays: evidence, indications, and reasonable use.
(J Am Heart Assoc, 2014-01-27) -
Long-term safety and efficacy of eculizumab in generalized myasthenia gravis.
(Muscle & nerve, 2019-07)<h4>Introduction</h4>Eculizumab is effective and well tolerated in patients with antiacetylcholine receptor antibody-positive refractory generalized myasthenia gravis (gMG; REGAIN; NCT01997229). We report an interim analysis ... -
Loss of dynamic regulation of G protein-coupled receptor kinase 2 by nitric oxide leads to cardiovascular dysfunction with aging.
(American journal of physiology. Heart and circulatory physiology, 2020-05)Nitric oxide (NO) and S-nitrosothiol (SNO) are considered cardio- and vasoprotective substances. We now understand that one mechanism in which NO/SNOs provide cardiovascular protection is through their direct inhibition ... -
Mechanical circulatory support for end-stage heart failure in repaired and palliated congenital heart disease.
(Current cardiology reviews, 2011-05)Approximately one in one hundred children is born with congenital heart disease. Most can be managed with corrective or palliative surgery but a small group will develop severe heart failure, leaving cardiac transplantation ... -
Multicomorbidity of chronic diseases and substance use disorders and their association with hospitalization: Results from electronic health records data.
(Drug and alcohol dependence, 2018-11)BACKGROUND:Chronic diseases are prevalent and the leading causes of mortality. Comorbidity of substance use disorders (SUDs) and chronic diseases is understudied to inform behavioral healthcare integration. OBJECTIVES:This ... -
Practice-Level Variation in Outpatient Cardiac Care and Association With Outcomes.
(J Am Heart Assoc, 2016-02-23)BACKGROUND: Utilization of cardiac services varies across regions and hospitals, yet little is known regarding variation in the intensity of outpatient cardiac care across cardiology physician practices or the association ... -
Pretargeting and Bioorthogonal Click Chemistry-Mediated Endogenous Stem Cell Homing for Heart Repair.
(ACS nano, 2018-12)Stem cell therapy is one of the promising strategies for the treatment of ischemic heart disease. However, the clinical application of stem cells transplantation is limited by low cell engraftment in the infarcted myocardium. ... -
Pulmonary vein isolation for the treatment of drug-refractory atrial fibrillation in adults with congenital heart disease.
(Congenit Heart Dis, 2012-07)BACKGROUND: Atrial fibrillation (AF) is a common arrhythmia in adults with congenital heart disease (CHD). Long-term antiarrhythmic therapy (AAT) in these patients has significant shortcomings. The safety and efficacy of ... -
Trade-offs in the effects of the apolipoprotein E polymorphism on risks of diseases of the heart, cancer, and neurodegenerative disorders: insights on mechanisms from the Long Life Family Study.
(Rejuvenation Res, 2015-04)The lack of evolutionary established mechanisms linking genes to age-related traits makes the problem of genetic susceptibility to health span inherently complex. One complicating factor is genetic trade-off. Here we focused ...
