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Browsing by Subject "Hepatic Stellate Cells"
Now showing items 1-4 of 4
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Hepatic stellate cells express thymosin Beta 4 in chronically damaged liver.
(PLoS One, 2015)Although the various biological roles of thymosin β4 (Tβ4) have been studied widely, the effect of Tβ4 and Tβ4-expressing cells in the liver remains unclear. Therefore, we investigated the expression and function of Tβ4 ... -
Increased Glutaminolysis Marks Active Scarring in Nonalcoholic Steatohepatitis Progression.
(Cellular and molecular gastroenterology and hepatology, 2020-01)<h4>Background & aims</h4>Nonalcoholic steatohepatitis (NASH) occurs in the context of aberrant metabolism. Glutaminolysis is required for metabolic reprograming of hepatic stellate cells (HSCs) and liver fibrogenesis in ... -
Schistosome-induced cholangiocyte proliferation and osteopontin secretion correlate with fibrosis and portal hypertension in human and murine schistosomiasis mansoni.
(Clin Sci (Lond), 2015-11)Schistosomiasis is a major cause of portal hypertension worldwide. It associates with portal fibrosis that develops during chronic infection. The mechanisms by which the pathogen evokes these host responses remain unclear. ... -
The transcriptomic response of rat hepatic stellate cells to endotoxin: implications for hepatic inflammation and immune regulation.
(PloS one, 2013-01)With their location in the perisinusoidal space of Disse, hepatic stellate cells (HSCs) communicate with all of the liver cell types both by physical association (cell body as well as cytosolic processes penetrating into ...
